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1.
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Brain networks are continuously modified throughout development, yet this plasticity can also make functional networks vulnerable to early life stress. Little is currentl [...]
19 March 2024 |
Psychology |
Article |
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2.
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Dendritic mechanisms driving input-output transformation in starburst amacrine cells (SACs) are not fully understood. Here, we combine two-photon subcellular voltage and [...]
28 February 2024 |
Biophysical Sciences; Computational Neuroscience; Neurobiology |
Article |
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3.
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Netrins dictate attractive and repulsive responses during axon growth and cell migration, where the presence of the receptor Uncoordinated-5 (UNC-5) on target cells resul [...]
16 February 2024 |
Biochemistry and Molecular Biology |
Article |
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4.
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Lysosomal calcium (Ca<sup>2+</sup>) release is critical to cell signaling and is mediated by well-known lysosomal Ca<sup>2+</sup> channels. Yet, h [...]
14 February 2024 |
Chemistry |
Article |
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5.
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Implicit biases - differential attitudes towards members of distinct groups - are pervasive in human societies and create inequities across many aspects of life. Recent r [...]
06 February 2024 |
Ecology and Evolution; Psychology |
Article |
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6.
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Task demands can differentially engage two fundamental attention components: selectivity (spatial bias) and effort (total nonselective attentional intensity). The relativ [...]
10 June 2022 |
Neurobiology |
Article |
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7.
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Dynamin-related protein 1 (Drp1) is a cytosolic GTPase protein that when activated translocates to the mitochondria, meditating mitochondrial fission and increasing react [...]
22 December 2023 |
Medicine |
Article |
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8.
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When multiple stimuli appear together in the receptive field of a visual cortical neuron, the response is typically close to the average of that neuron’s response to ea [...]
18 December 2023 |
Computational Neuroscience; Neurobiology |
Article |
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9.
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Prestin responds to transmembrane voltage fluctuations by changing its cross-sectional area, a process underlying the electromotility of outer hair cells and cochlear amp [...]
06 December 2023 |
Biochemistry and Molecular Biology |
Article |
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10.
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To become and remain functional, individual neuron types must select during development and maintain throughout life their distinct terminal identity features, such as ex [...]
03 January 2020 |
Development, Regeneration, and Stem Cell Biology; Neurobiology; Neurology |
Article |
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11.
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Terminal selectors are transcription factors (TFs) that establish during development and maintain throughout life post-mitotic neuronal identity. We previously showed tha [...]
01 October 2020 |
Development, Regeneration, and Stem Cell Biology; Neurobiology |
Article |
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12.
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Spinal motor neurons (MNs) constitute cellular substrates for several movement disorders. Although their early development has received much attention, how spinal MNs bec [...]
22 March 2022 |
Neurobiology |
Article |
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13.
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Spatially distributed excitation and inhibition collectively shape a visual neuron’s receptive field (RF) properties. In the direction-selective circuit of the mammalia [...]
07 June 2021 |
Biophysical Sciences; Neurobiology; Organismal Biology and Anatomy |
Article |
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14.
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Low-dimensional linear dynamics are observed in neuronal population activity in primary motor cortex (M1) when monkeys make reaching movements. This population-level beha [...]
17 November 2020 |
Computational Neuroscience; Organismal Biology and Anatomy |
Article |
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15.
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How circuits self-assemble starting from neuronal stem cells is a fundamental question in developmental neurobiology. Here, we addressed how neurons from different stem c [...]
20 June 2022 |
Computational Neuroscience; Molecular Genetics and Cell Biology; Neurobiology |
Article |
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16.
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How circuits assemble starting from stem cells is a fundamental question in developmental neurobiology. We test the hypothesis that, in neuronal stem cells, temporal tran [...]
10 September 2019 |
Molecular Genetics and Cell Biology |
Article |
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17.
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How circuit wiring is specified is a key question in developmental neurobiology. Previously, using the Drosophila motor system as a model, we found the classic temporal t [...]
11 May 2020 |
Development, Regeneration, and Stem Cell Biology; Molecular Genetics and Cell Biology |
Article |
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18.
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Decisions about the behavioral significance of sensory stimuli often require comparing sensory inference of what we are looking at to internal models of what we are looki [...]
18 April 2017 |
Neurobiology |
Article |
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19.
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Comparing sequential stimuli is crucial for guiding complex behaviors. To understand mechanisms underlying sequential decisions, we compared neuronal responses in the pre [...]
07 September 2021 |
Neurobiology |
Article |
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20.
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In the interest of advocating for the postdoctoral community in the United States (US), we compared the results of surveys of postdocs carried out in 2019 and in late 202 [...]
26 July 2022 |
Ben May Department for Cancer Research; Biochemistry and Molecular Biology; Human Genetics; Neurobiology; Pediatrics |
Article |
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21.
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A hexanucleotide repeat expansion in C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). A hallmark of ALS/ [...]
07 September 2023 |
Neurobiology; Neurology |
Article |
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22.
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The primary motor (M1) and somatosensory (S1) cortices play critical roles in motor control but the signaling between these structures is poorly understood. To fill this [...]
10 November 2023 |
Computational Neuroscience; Neurological Surgery; Organismal Biology and Anatomy |
Article |
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23.
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It is commonly assumed that cities are detrimental to mental health. However, the evidence remains inconsistent and at most, makes the case for differences between rural [...]
27 July 2021 |
Ecology and Evolution; Psychology; Public Health Sciences |
Article |
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24.
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Lysosomes adopt dynamic, tubular states that regulate antigen presentation, phagosome resolution, and autophagy. Tubular lysosomes are studied either by inducing autophag [...]
04 October 2021 |
Ben May Department for Cancer Research; Cancer Biology; Chemistry |
Article |
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25.
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Sleep is critical to a variety of cognitive functions and insufficient sleep can have negative consequences for mood and behavior across the lifespan. An important open q [...]
02 November 2023 |
Psychology |
Article |
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