|
1.
|
In coastal marine ecosystems, kelp forests serve as a vital habitat for numerous species and significantly influence local nutrient cycles. Bull kelp, or Nereocystis luet [...]
22 May 2024 |
Biophysical Sciences; Ecology and Evolution; Microbiology |
Article |
|
|
2.
|
Commensal microbes have the capacity to affect development and severity of autoimmune diseases. Germ-free (GF) animals have proven to be a fine tool to obtain definitive [...]
08 May 2024 |
Cancer Biology; Immunology; Microbiology; Pathology |
Article |
|
|
3.
|
Interleukin-1 (IL-1) signaling is essential for controlling virulent Mycobacterium tuberculosis (Mtb) infection since antagonism of this pathway leads to exacerbated path [...]
11 April 2024 |
Microbiology |
Article |
|
|
4.
|
The vast diversity of mammalian adaptive antigen receptors allows for robust and efficient immune responses against a wide number of pathogens. The antigen receptor reper [...]
04 March 2024 |
Genetics, Genomics, and Systems Biology; Immunology; Microbiology |
Article |
|
|
5.
|
Plasmids are extrachromosomal genetic elements that often encode fitness-enhancing features. However, many bacteria carry “cryptic” plasmids that do not confer clear [...]
29 February 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences; Medicine; Microbiology |
Article |
|
|
6.
|
Sophisticated gene circuits built by synthetic biology can enable bacteria to sense their environment and respond predictably. Engineered biosensing bacteria outfitted wi [...]
07 March 2024 |
Microbiology |
Article |
|
|
7.
|
Plasmids alter microbial evolution and lifestyles by mobilizing genes that often confer fitness in changing environments across clades. Yet our ecological and evolutionar [...]
04 March 2024 |
Medicine; Microbiology |
Article |
|
|
8.
|
Hepatitis C virus (HCV) has no animal reservoir, infecting only humans. To investigate species barrier determinants limiting infection of rodents, murine liver complement [...]
04 November 2020 |
Microbiology |
Article |
|
|
9.
|
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ongoing coronavirus disease 2019 (COVID-19) pandemic underscores the need for new treatment [...]
20 January 2022 |
Ben May Department for Cancer Research; Chemistry; Microbiology; Pathology; Surgery |
Article |
|
|
10.
|
Yersinia pestis is the causative agent of the plague. Y. pestis KIM 10+ strain was passaged and selected for loss of the 102 kb pgm locus, r [...]
29 April 2011 |
Microbiology |
Article |
|
|
11.
|
Pathogenic Yersinia species possess a type III secretion system, which is required for the delivery of effector Yop proteins into target cells during infectio [...]
30 March 2012 |
Microbiology |
Article |
|
|
12.
|
In natural environments, bacteria often adhere to surfaces where they form complex multicellular communities. Surface adherence is determined by the biochemical compos [...]
23 January 2014 |
Biochemistry and Molecular Biology; Microbiology |
Article |
|
|
13.
|
Legionella pneumophila, the causative agent of Legionnaires' disease, invades and replicates within macrophages and protozoan cells inside a vacuole. The type [...]
23 February 2012 |
Microbiology |
Article |
|
|
14.
|
Acquisition of iron is necessary for the replication of nearly all bacterial pathogens; however, iron of vertebrate hosts is mostly sequestered by heme and bound to he [...]
22 August 2008 |
Microbiology |
Article |
|
|
15.
|
Staphylococcus aureus infection is a frequent cause of sepsis in humans, a disease associated with high mortality and without specific intervention. When susp [...]
20 October 2011 |
Microbiology |
Article |
|
|
16.
|
The bacterial pathogen Staphylococcus aureus seeds abscesses in host tissues to replicate at the center of these lesions, protected from host immune cells via [...]
05 August 2010 |
Microbiology |
Article |
|
|
17.
|
The current model of hepatitis C virus (HCV) production involves the assembly of virions on or near the surface of lipid droplets, envelopment at the ER in association [...]
05 January 2012 |
Microbiology |
Article |
|
|
18.
|
Hepatitis C virus (HCV) enters hepatocytes following a complex set of receptor interactions, culminating in internalization via clathrin-mediated endocytosis. However, [...]
24 December 2009 |
Microbiology |
Article |
|
|
19.
|
Candida albicans is an opportunistic pathogen that proliferates in the intestinal tract of critically ill patients where it continues to be a major cause of i [...]
13 January 2012 |
Immunology; Microbiology; Surgery |
Article |
|
|
20.
|
Septal membranes of Staphylococcus aureus serve as the site of secretion for precursors endowed with the YSIRK motif. Depletion of ltaS, a gene required for lipoteichoic [...]
04 January 2024 |
Microbiology |
Article |
|
|
21.
|
We have experimentally and computationally defined a set of genes that form a conserved metabolic module in the α-proteobacterium Caulobacter crescentus and [...]
19 December 2008 |
Biochemistry and Molecular Biology; Biophysical Sciences; Microbiology |
Article |
|
|
22.
|
The multi-step process of hepatitis C virus (HCV) entry is facilitated by various host factors, including epidermal growth factor receptor (EGFR) and the tight junction p [...]
29 December 2023 |
Microbiology |
Article |
|
|
23.
|
In both prokaryotic and eukaryotic cells, gene expression is regulated across the cell cycle to ensure “just-in-time” assembly of select cellular structures and mo [...]
14 August 2009 |
Biochemistry and Molecular Biology; Microbiology |
Article |
|
|
24.
|
Pairwise interactions are often used to predict features of complex microbial communities due to the challenge of measuring multi-species interactions in high dimensional [...]
07 December 2023 |
Microbiology |
Article |
|
|
25.
|
Surface proteins of Staphylococcus aureus are secreted across septal membranes for assembly into the bacterial cross-wall. This localized secretion requires the YSIRK/GXX [...]
14 May 2018 |
Microbiology |
Article |
|
