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1.
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The activation of the stimulator of interferon genes (STING) protein by cyclic dinucleotide metabolites plays a critical role in antitumor immunity. However, synthetic ST [...]
07 October 2024 |
Chemistry[...] |
Article |
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2.
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Cholesterol is an essential membrane component, and the metabolites from cholesterol play important biological functions to intricately support cancer progression and dam [...]
15 August 2024 |
Article |
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3.
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The efficacy of radiotherapy (RT) is limited by inefficient X-ray absorption and reactive oxygen species generation, upregulation of immunosuppressive factors, and a redu [...]
10 September 2024 |
Chemistry; Radiation and Cellular Oncology |
Article |
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4.
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The performance of photodynamic therapy (PDT) depends on the solubility, pharmacokinetic behaviors, and photophysical properties of photosensitizers (PSs). However, highl [...]
23 August 2021 |
Chemistry; Radiation and Cellular Oncology |
Article |
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5.
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Abnormal cancer metabolism causes hypoxic and immunosuppressive tumor microenvironment (TME), which limits the antitumor efficacy of photodynamic therapy (PDT). Herein, w [...]
25 June 2024 |
Chemistry; Radiation and Cellular Oncology |
Article |
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6.
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Recent studies have linked elevated tumor aneuploidy to anti-tumor immune suppression and adverse survival following immunotherapy. Herein, we provide supportive evidence [...]
21 August 2024 |
Radiation and Cellular Oncology |
Article |
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7.
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The combination of cuproptosis and immune checkpoint inhibition has shown promise in treating malignant tumors. However, it remains a challenge to deliver copper ions and [...]
16 July 2024 |
Chemistry; Radiation and Cellular Oncology |
Article |
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8.
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Cellular senescence has been increasingly recognized as a hallmark of cancer, reflecting its association with aging and inflammation, its role as a response to deregulate [...]
30 July 2024 |
Molecular Genetics and Cell Biology |
Article |
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9.
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The low success rate of cancer nanomedicines has raised debate on the role of the enhanced permeability and retention (EPR) effect on tumor deposition of nanotherapeutics [...]
17 July 2024 |
Chemistry; Radiation and Cellular Oncology |
Article |
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10.
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Chemoradiotherapy combines radiotherapy with concurrent chemotherapy to potentiate antitumor activity but exacerbates toxicities and causes debilitating side effects in c [...]
21 February 2024 |
Chemistry; Radiation and Cellular Oncology |
Article |
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11.
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Cancer vaccines have been actively pursued to bolster antitumor immunity. Here, we designed nanoscale metal-organic frameworks (nMOFs) as locally activable immunotherapeu [...]
02 October 2020 |
Chemistry; Radiation and Cellular Oncology |
Article |
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12.
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These studies define a new mechanism-based approach to radiosensitize tumor cure by single dose radiotherapy (SDRT). Published evidence indicates that SDRT induces acu [...]
02 August 2013 |
Radiation and Cellular Oncology |
Article |
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13.
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Previous reports have implicated an induction of genes in IFN/STAT1 (Interferon/STAT1) signaling in radiation resistant and prosurvival tumor phenotypes in a number of [...]
05 January 2012 |
Radiation and Cellular Oncology |
Article |
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14.
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Rationale: Strategies to stage and treat cancer rely on a presumption of either localized or widespread metastatic disease. An intermediate state of metastasis termed [...]
10 December 2012 |
Medicine; Radiation and Cellular Oncology; Surgery |
Article |
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15.
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Background: Cancer staging and treatment presumes a division into localized or metastatic disease. We proposed an intermediate state defined by ≤5 cumulative metasta [...]
13 December 2011 |
Cancer Biology; Pathology; Radiation and Cellular Oncology; Surgery |
Article |
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16.
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No abstract
02 January 2024 |
Radiation and Cellular Oncology |
Article |
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17.
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As heavy-metal-based nanoscale metal–organic frameworks (nMOFs) are excellent radiosensitizers for radiotherapy via enhanced energy deposition and reactive oxygen speci [...]
15 August 2023 |
Chemistry; Radiation and Cellular Oncology |
Article |
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18.
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Intimal hyperplasia (IH) is the primary cause of vein bypass graft failure. The smooth muscle cell (SMC) is a key element of IH as it phenotypically switches from a contr [...]
01 July 2015 |
Radiation and Cellular Oncology; Surgery |
Article |
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19.
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Cancer cells alter mechanical tension in their cell membranes. New interventions to regulate cell membrane tension present a potential strategy for cancer therapy. Herein [...]
27 August 2023 |
Chemistry; Radiation and Cellular Oncology |
Article |
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20.
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Statins, a class of HMG-CoA reductase inhibitors best known for their cholesterol-reducing and cardiovascular protective activity, have also demonstrated promise in cance [...]
03 August 2023 |
Molecular Genetics and Cell Biology |
Article |
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21.
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Although sonodynamic therapy (SDT) has shown promise for cancer treatment, the lack of efficient sonosensitizers (SSs) has limited the clinical application of SDT. Here, [...]
25 February 2023 |
Chemistry; Radiation and Cellular Oncology |
Article |
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22.
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Long-circulating nanomedicines efficiently deliver chemotherapies to tumors to reduce general toxicity. However, extended blood circulation of nanomedicines can increase [...]
16 November 2022 |
Radiation and Cellular Oncology; Radiology |
Article |
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