All original data for the SU2C-MARK Foundation cohort are available from the original manuscript’s Zenodo repository: https://zenodo.org/records/7849582. All data for the MSK-IMPACT cohort is deposited at the following cBioPortal repository: https://www.cbioportal.org/study/summary?id=tmb_mskcc_2018 and AACR Project GENIE: https://www.synapse.org/#!Synapse:syn7222066/wiki/405659. All modified and/or newly generated data are available at this manuscript’s associated Zenodo repository: https://zenodo.org/records/11671610.

All proprietary code necessary to replicate the results and figures in this manuscript are available at this manuscript’s associated Zenodo repository: https://zenodo.org/records/11671610.

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