1.
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Gamma/delta (γδ) T cells are unconventional lymphocytes that recognize diverse ligands via somatically recombined T cell antigen receptors (γδ TCRs). The molecular me [...]
13 September 2024 |
Biochemistry and Molecular Biology |
Article |
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2.
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Many applications in chemistry, biology, and energy storage/conversion research rely on molecular simulations to provide fundamental insight into structural and transport [...]
29 May 2019 |
Biochemistry and Molecular Biology |
Article |
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3.
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Algae, plants, bacteria, and fungi contain flavin-binding light-oxygen-voltage (LOV) domains that function as blue light sensors to control cellular responses to light. I [...]
15 January 2019 |
Biochemistry and Molecular Biology |
Article |
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4.
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The use of trivalent erbium (Er 3+), typically embedded as an atomic defect in the solid-state, has widespread adoption as a dopant in telecommunication devices [...]
27 March 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences |
Article |
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5.
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Using synchrotron radiation, diffraction data extending to 0.70 Å resolution were collected from crystals of the small protein crambin at room temperature (297 K) [...]
27 August 2024 |
Biochemistry and Molecular Biology |
Article |
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6.
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The fine tuning of biological electrical signaling is mediated by variations in the rates of opening and closing of gates that control ion flux through different ion chan [...]
29 August 2024 |
Biochemistry and Molecular Biology |
Article |
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7.
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Recent studies have suggested that mRNA internal m 7G and its writer protein METTL1 are closely related to cell metabolism and cancer regulation. Here, we ident [...]
28 August 2024 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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8.
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Coded ribosomal peptide synthesis could not have evolved unless its sequence and amino acid–specific aminoacylated tRNA substrates already existed. We therefore wondere [...]
23 August 2024 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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9.
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The reversible association of transmembrane helices is a fundamental mechanism in how living cells convey information and respond to physiological events. The cardiac cal [...]
06 August 2024 |
Biochemistry and Molecular Biology |
Article |
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10.
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Cis-regulatory elements (CREs) are pivotal in orchestrating gene expression throughout diverse biological systems. Accurate identification and in-depth characterization o [...]
10 August 2024 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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11.
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T-box riboswitches are noncoding RNA elements involved in genetic regulation of most Gram-positive bacteria. They regulate amino acid metabolism by assessing the aminoacy [...]
03 August 2024 |
Biochemistry and Molecular Biology |
Article |
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12.
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When cells experience stress, they undergo a number of dramatic intracellular molecular changes. One of these changes is the formation of biomolecular condensates, or [...]
2024-08 |
Biochemistry and Molecular Biology |
Dissertation |
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13.
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2-Hydroxyacyl-CoA lyase/synthase (HACL/S) is a thiamine diphosphate (ThDP)-dependent versatile enzyme originally discovered in the mammalian α-oxidation pathway. HACL/S [...]
21 July 2024 |
Biochemistry and Molecular Biology |
Article |
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14.
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The protein translocon at the endoplasmic reticulum comprises the Sec61 translocation channel and numerous accessory factors that collectively facilitate the biogenesis o [...]
18 June 2024 |
Biochemistry and Molecular Biology; Molecular Genetics and Cell Biology |
Article |
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15.
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The ATP-binding cassette (ABC) transporter, MsbA, plays a pivotal role in lipopolysaccharide (LPS) biogenesis by facilitating the transport of the LPS precursor lipooligo [...]
15 July 2024 |
Biochemistry and Molecular Biology |
Article |
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16.
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N6-methyladenosine (m 6A) plays critical roles in regulating mRNA metabolism. However, comprehensive m 6A methylomes in different pl [...]
07 June 2024 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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17.
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Almost all elongator tRNAs (Transfer RNAs) harbor 5-methyluridine 54 and pseudouridine 55 in the T arm, generated by the enzymes TrmA and TruB, respectively, in Escherich [...]
18 June 2024 |
Biochemistry and Molecular Biology; Molecular Genetics and Cell Biology |
Article |
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18.
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A protein’s genetic architecture – the set of causal rules by which its sequence produces its functions – also determines its possible evolutionary trajectories. Pr [...]
20 May 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences; Ecology and Evolution; Genetics, Genomics, and Systems Biology; Human Genetics |
Article |
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19.
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Vasodilator-stimulated phosphoprotein (VASP) family proteins play a crucial role in mediating the actin network architecture in the cytoskeleton. The Ena/VASP homology 2 [...]
22 April 2024 |
Biochemistry and Molecular Biology; Chemistry; Molecular Genetics and Cell Biology |
Article |
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20.
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Proteins are molecular machines and to understand how they work, we need to understand how they move. New pump-probe time-resolved X-ray diffraction methods open up ways [...]
15 April 2024 |
Biochemistry and Molecular Biology; Ecology and Evolution |
Article |
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21.
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RNA molecules often play critical roles in assisting the formation of membraneless organelles in eukaryotic cells. Yet, little is known about the organization of RNAs wit [...]
27 March 2024 |
Biochemistry and Molecular Biology; Biological Sciences; Biophysical Sciences; Physics |
Article |
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22.
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Cells must sense and respond to sudden maladaptive environmental changes—stresses—to survive and thrive. Across eukaryotes, stresses such as heat shock trigger conser [...]
11 April 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences; Genetics, Genomics, and Systems Biology; Medicine |
Article |
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23.
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Despite the generally accepted role of the hydrophobic effect as the driving force for folding, many intrinsically disordered proteins (IDPs), including those with hydrop [...]
12 April 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences |
Article |
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24.
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No abstract
02 April 2024 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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25.
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Several physical mechanisms have been proposed to explain allostery in proteins. They differ by the number of internal states that they assume a protein to occupy, leavin [...]
09 November 2023 |
Biochemistry and Molecular Biology; Biophysical Sciences |
Article |
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