Biochemistry and Molecular Biology

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Biochemistry and Molecular Biology	285 records found 1 - 25	Search took 0.18 seconds.

1.	Multiple Files Engineered-protein-G-variants-for-multifunctional-antibody-based-assemblies Engineered protein G variants for multifunctional antibody-based assemblies Slezak, Tomasz ; O'Leary, Kelly M. ; Li, Jinyang ; Rohaim, Ahmed ; Davydova, Elena K. ; Kossiak[...] We have developed a portfolio of antibody-based modules that can be prefabricated as standalone units and snapped together in plug-and-play fashion to create uniquely pow [...] 25 January 2025 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
2.	Multiple Files riso-et-al-2024-binding-mode-guided-development-of-high-performance-antibodies-targeting-site-specific Binding mode–guided development of high-performance antibodies targeting site-specific posttranslational modifications Riso, Mariapia ; Shah, Rohan N. ; Koide, Akiko ; Ruthenburg, Alexander J. ; Koide, Shohei ; Hat[...] Posttranslational modifications (PTMs) of proteins play critical roles in regulating many cellular events. Antibodies targeting site-specific PTMs are essential tools for [...] 30 December 2024 \| Biochemistry and Molecular Biology[...] \| Article \| Detailed record - Similar records
3.	Multiple Files Programming-scheduled-self-assembly-of-circadian-materials Programming scheduled self-assembly of circadian materials Leech, Gregor ; Melcher, Lauren ; Chiu, Michelle ; Nugent, Maya ; Juliano, Shirlaine ; Burton, [...] Active biological molecules present a powerful, yet largely untapped, opportunity to impart autonomous regulation of materials. Because these systems can function robustl [...] 02 January 2025 \| Biochemistry and Molecular Biology[...] \| Article \| Detailed record - Similar records
4.	PDF Deeper-Meaning-of-the-2024-Nobel-Prize-in-Physiology-or-Medicine The Deeper Meaning of the 2024 Nobel Prize in Physiology or Medicine Shapiro, James A. No abstract 20 December 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
5.	Multiple Files Recent-advances-in-the-structure-function-and-regulation Recent advances in the structure, function and regulation of the volume-regulated anion channels and their role in immunity Yanushkevich, Sergei ; Zieminska, Aleksandra ; Gonzalez, Joshua ; Añazco, Francisca ; Song, [...] Volume-regulated anion channels (VRACs) are heteromeric complexes formed by proteins of the leucine-rich repeat-containing 8 (LRRC8) family. LRRC8A (also known as SWELL1) [...] 22 December 2024 \| Biochemistry and Molecular Biology[...] \| Article \| Detailed record - Similar records
6.	Multiple Files Phytosulfokine-downregulates-defense-related-WRKY-transcription-factors Phytosulfokine downregulates defense-related WRKY transcription factors and attenuates pathogen-associated molecular pattern-triggered immunity Liu, Dian ; Jelenska, Joanna ; Morgan, Jessica M. ; Greenberg, Jean T. Phytosulfokine (PSK) is a plant growth-promoting peptide hormone that is perceived by its cell surface receptors PSKR1 and PSKR2 in Arabidopsis. Plants lacking the PSK re [...] 11 December 2024 \| Biochemistry and Molecular Biology[...] \| Article \| Detailed record - Similar records
7.	Multiple Files cui-et-al-2024-targeting-dtx2-ufd1-mediated-fto-degradation-to-regulate-antitumor-immunity Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity Cui, Yan-Hong ; Wei, Jiangbo ; Fan, Hao ; Li, Wenlong ; Zhao, Lijie ; Wilkinson, Emma ; Peterson, [...] Here, we show that vitamin E succinate (VES) acts as a degrader for the m6A RNA demethylase fat mass and obesity-associated protein (FTO), thus suppressing tumor growth a [...] 11 December 2024 \| Biochemistry and Molecular Biology[...] \| Article \| Detailed record - Similar records
8.	Multiple Files Conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-GPCR-function Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function Kordon, Szymon P. ; Cechova, Kristina ; Bandekar, Sumit J. ; Leon, Katherine ; Dutka, Przemy[...] Adhesion G Protein-Coupled Receptors (aGPCRs) are key cell-adhesion molecules involved in numerous physiological functions. aGPCRs have large multi-domain extracellular r [...] 04 December 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
9.	PDF How-active-cholesterol-coordinates-cell-cholesterol-homeostasis How active cholesterol coordinates cell cholesterol homeostasis: Test of a hypothesis Lange, Yvonne ; Steck, Theodore L. How do cells coordinate the diverse elements that regulate their cholesterol homeostasis? Our model postulates that membrane cholesterol forms simple complexes with bilay [...] 02 November 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
10.	Multiple Files elife-90603-v1 Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin Shangguan, Julia ; Rock, Ronald S. Myosin 10 (Myo10) is a motor protein known for its role in filopodia formation. Although Myo10-driven filopodial dynamics have been characterized, there is no information [...] 31 October 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
11.	Multiple Files Variable-orthogonality-of-serine-integrase-interactions-within-the-ϕC31-family Variable orthogonality of serine integrase interactions within the ϕC31 family MacDonald, Alasdair I. ; Baksh, Aron ; Holland, Alexandria ; Shin, Heewhan ; Rice, Phoebe A. ; [...] Serine integrases are phage- (or mobile element-) encoded enzymes that catalyse site-specific recombination reactions between a short DNA sequence on the phage genome (at [...] 01 November 2024 \| Article \| Detailed record - Similar records
12.	Multiple Files sciadv.adp7727 Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency Wu, Jinjun ; Xiao, Yu ; Liu, Yunzheng ; Wen, Li ; Jin, Chuanyang ; Liu, Shun ; Paul, Sneha ; He, Chua[...] Nuclear speckles are nuclear membraneless organelles in higher eukaryotic cells playing a vital role in gene expression. Using an in situ reverse transcription–based se [...] 16 October 2024 \| Biochemistry and Molecular Biology; Chemistry; Physics \| Article \| Detailed record - Similar records
13.	Multiple Files Elucidation-of-the-noncovalent-interactions-driving-enzyme-activity Elucidation of the noncovalent interactions driving enzyme activity guides branching enzyme engineering for α-glucan modification Zong, Zhiyou ; Zhang, Xuewen ; Chen, Peng ; Fu, Zhuoyue ; Zeng, Yan ; Wang, Qian ; Chipot, Christo[...] Branching enzymes (BEs) confer to α-glucans, the primary energy-storage reservoir in nature, a variety of features, like slow digestion. The full catalytic cycle of BEs [...] 09 October 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
14.	Multiple Files RNA-m5C-oxidation-by-TET2-regulates-chromatin-state-and-leukaemogenesis RNA m<sup>5</sup>C oxidation by TET2 regulates chromatin state and leukaemogenesis Zou, Zhongyu ; Dou, Xiaoyang ; Li, Ying ; Zhang, Zijie ; Wang, Juan ; Gao, Boyang ; Xiao, Yu ; Wang, [...] Mutation of tet methylcytosine dioxygenase 2 (encoded by TET2) drives myeloid malignancy initiation and progression. TET2 deficiency is known to cause a globally opened c [...] 02 October 2024 \| Biochemistry and Molecular Biology; Chemistry \| Article \| Detailed record - Similar records
15.	Multiple Files wilson-et-al-2024-the-role-of-general-acid-catalysis-in-the-mechanism-of-an-alkyl-transferase-ribozyme The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme Wilson, Timothy J. ; McCarthy, Erika ; Ekesan, Şölen ; Giese, Timothy J. ; Li, Nan-Sheng ; Hu[...] MTR1 is an in vitro-selected alkyl transferase ribozyme that transfers an alkyl group from O⁶-alkylguanine to N1 of the target adenine in the RNA substrate (A6 [...] 02 October 2024 \| Biochemistry and Molecular Biology; Chemistry \| Article \| Detailed record - Similar records
16.	Multiple Files Structural-insights-into-translocation-and-tailored-synthesis-of-hyaluronan Structural insights into translocation and tailored synthesis of hyaluronan Górniak, Ireneusz ; Stephens, Zachery ; Erramilli, Satchal K. ; Gawda, Tomasz ; Kossiakoff,[...] Hyaluronan (HA) is an essential component of the vertebrate extracellular matrix. It is a heteropolysaccharide of N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcA) [...] 25 September 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
17.	Multiple Files Ligand-induced-segregation-from-large-cell-surface-phosphatases-is-a-critical-step-in-γδ-TCR-triggering Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering Li, Fenglei ; Roy, Sobhan ; Niculcea, Jacob ; Gould, Keith ; Adams, Erin J. ; van der Merwe, P.[...] Gamma/delta (γδ) T cells are unconventional lymphocytes that recognize diverse ligands via somatically recombined T cell antigen receptors (γδ TCRs). The molecular me [...] 13 September 2024 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
18.	PDF roux-2021-string-method-with-swarms-of-trajectories-mean-drifts-lag-time-and-committor String Method with Swarms-of-Trajectories, Mean Drifts, Lag Time, and Committor Roux, Benoît The kinetics of a dynamical system comprising two metastable states is formulated in terms of a finite-time propagator in phase space (position and velocity) adapted to t [...] 18 August 2021 \| Biochemistry and Molecular Biology; Chemistry \| Article \| Detailed record - Similar records
19.	Multiple Files li-et-al-2021-synthesis-of-oligoribonucleotides-containing-a-2-amino-5-s-phosphorothiolate-linkage Synthesis of Oligoribonucleotides Containing a 2′-Amino-5′-S-phosphorothiolate Linkage Li, Nan-Sheng ; Koo, Selene C. ; Piccirilli, Joseph A. Oligoribonucleotides containing a photocaged 2′-amino-5′-S-phophorothiolate linkage have potential applications as therapeutic agents and biological probes to investi [...] 17 September 2021 \| Biochemistry and Molecular Biology; Chemistry \| Article \| Detailed record - Similar records
20.	Multiple Files roman-et-al-2021-the-sars-cov-2-programmed-1-ribosomal-frameshifting-element-crystal-structure-solved-to-2-09-å-using The SARS-CoV-2 Programmed −1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography Roman, Christina ; Lewicka, Anna ; Koirala, Deepak ; Li, Nan-Sheng ; Piccirilli, Joseph A. The programmed −1 ribosomal frameshifting element (PFSE) of SARS-CoV-2 is a well conserved structured RNA found in all coronaviruses’ genomes. By adopting a pseudokno [...] 30 July 2021 \| Biochemistry and Molecular Biology; Chemistry \| Article \| Detailed record - Similar records
21.	Multiple Files toparlak-et-al-2023-cyclophospholipids-enable-a-protocellular-life-cycle Cyclophospholipids Enable a Protocellular Life Cycle Toparlak, Ö. Duhan ; Sebastianelli, Lorenzo ; Ortuno, Veronica Egas ; Karki, Megha ; Xing, [...] There is currently no plausible path for the emergence of a self-replicating protocell, because prevalent formulations of model protocells are built with fatty acid vesic [...] 01 December 2023 \| Biochemistry and Molecular Biology; Chemistry \| Article \| Detailed record - Similar records
22.	Multiple Files peng-et-al-2021-prediction-and-validation-of-a-protein-s-free-energy-surface-using-hydrogen-exchange-and-(importantly) Prediction and Validation of a Protein’s Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence Peng, Xiangda ; Baxa, Michael ; Faruk, Nabil ; Sachleben, Joseph R. ; Pintscher, Sebastian ; Ga[...] The denaturant dependence of hydrogen–deuterium exchange (HDX) is a powerful measurement to identify the breaking of individual H-bonds and map the free energy surface [...] 22 December 2021 \| Biochemistry and Molecular Biology; Biological Sciences; Biophysical Sciences; Chemistry \| Article \| Detailed record - Similar records
23.	PDF bedrov-et-al-2019-molecular-dynamics-simulations-of-ionic-liquids-and-electrolytes-using-polarizable-force-fields Molecular Dynamics Simulations of Ionic Liquids and Electrolytes Using Polarizable Force Fields Bedrov, Dmitry ; Piquemal, Jean-Philip ; Borodin, Oleg ; MacKerell, Alexander D. ; Roux, Ben[...] Many applications in chemistry, biology, and energy storage/conversion research rely on molecular simulations to provide fundamental insight into structural and transport [...] 29 May 2019 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
24.	PDF zayner-et-al-2019-helical-contributions-mediate-light-activated-conformational-change-in-the-lov2-domain-of-avena Helical Contributions Mediate Light-Activated Conformational Change in the LOV2 Domain of <i>Avena sativa</i> Phototropin 1 Zayner, Josiah P. ; Mathes, Tilo ; Sosnick, Tobin R. ; Kennis, John T. M. Algae, plants, bacteria, and fungi contain flavin-binding light-oxygen-voltage (LOV) domains that function as blue light sensors to control cellular responses to light. I [...] 15 January 2019 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
25.	Multiple Files ji-et-al-2024-nanocavity-mediated-purcell-enhancement-of-er-in-tio2-thin-films-grown-via-atomic-layer-deposition Nanocavity-Mediated Purcell Enhancement of Er in TiO<sub>2</sub> Thin Films Grown via Atomic Layer Deposition Ji, Cheng ; Solomon, Michael T. ; Grant, Gregory D. ; Tanaka, Koichi ; Hua, Muchuan ; Wen, Jian[...] The use of trivalent erbium (Er³⁺), typically embedded as an atomic defect in the solid-state, has widespread adoption as a dopant in telecommunication devices [...] 27 March 2024 \| Biochemistry and Molecular Biology; Biophysical Sciences \| Article \| Detailed record - Similar records

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