Background: Food insecurity is one of several household material hardships (HMH) recognized for their impact on disease severity and healthcare utilization in patients [...]

Importance: Food insecurity affects nearly 13.5% of US households and has worsened after the COVID-19 pandemic. However, the prevalence, associated factors, and impact [...]

Background: Participant discontinuation is a significant challenge in pharmacological trials for trichotillomania (hair-pulling disorder). Attrition in clinical trials [...]

The goal of this thesis is to develop cytokine therapies to reduce inflammation, promote tissue repair, and restore lost function in neuroinflammatory disease. To this en [...]

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful [...]

Multicellular organisms rely on their constituent cells to adopt distinct fates and maintain stable identities and functions. At the same time, cells retain a degree of f [...]

Walking cadence has been suggested as a measure of activity intensity; however, it remains uncertain if prefrail and frail older adults can increase their walking cadence [...]

We are witnessing a significant increase in complex T cell-mediated immune disorders, such as food allergies and autoimmune diseases, which are driven by diverse inflamma [...]

Introduction: Cardiovascular-kidney-metabolic (CKM) syndrome, driven by metabolic risk factors like obesity, type 2 diabetes (DM-2), chronic kidney disease (CKD), and [...]

Objectives: The residency match can be a stressful and costly period for applicants. A notable portion of applicants choose to apply to multiple specialties during the [...]

Introduction: In this qualitative study, we employ the construct of authoritative knowledge to better understand how birthing people prepare for breastfeeding experien [...]

Bacteria utilize bacteriocins as a mechanism to maintain a competitive advantage in their niche. Lantibiotic-producing bacteria have been investigated for their ability t [...]

C. difficile, a spore-forming anaerobe, is a leading infectious cause of nosocomial diarrhea. The clinical outlook for C. difficile associated disease (CDAD) is highly va [...]

Cells are enclosed by a membrane bilayer comprised of lipids and proteins. These membranes function to separate the extracellular environment from the internal cellular p [...]

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited treatment options. Distant metastasis is the leading cause of breast cancer de [...]

Purpose: Medical practice is complex, ambiguous and dynamic. It requires more than technical knowledge; it necessitates the application of wisdom. Unfortunately, integ [...]

Understanding how protein structure and function are determined by amino acid sequence is fundamental to biochemistry. Evolutionary biochemistry extends the classic seque [...]

Despite improvements in medical treatments, the global burden of cancer has steadily increased over time. Breast cancer remains the most frequently diagnosed malignancy i [...]

Introduction: Increasing research interest has focused on placental pathology and pregnancy outcomes. Placental pathology examinations that are requested by the delive [...]

Introduction: Surgical trainees spend key years of their reproductive potential in training. However, their family planning needs are seldom addressed and remain poorl [...]

Background: Spinal epidural abscess (SEA) is an uncommon but potentially life-threatening infection that requires prompt identification and treatment. Early SEAs may p [...]

Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates eukaryotic cell growth and metabolism in response to nutrient and growth fac [...]

Introduction: Dissociation involves a lapse in normal perception of reality or awareness; it has Q6 been associated with multiple psychiatric disorders and has been su [...]

Major histocompatibility complex-related protein 1 (MR1) is a highly conserved non-polymorphic antigen presenting protein that is well known for the presentation of micro [...]

Proteins undergo constant, thermally induced fluctuations in which hydrogen bonded structures unfold in events ranging from global unfolding to small scale events lik [...]