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Acute kidney injury (AKI) is a common syndrome in hospitalized patients and is associated with increased morbidity and mortality. The focus of AKI care requires a shift a [...]
29 October 2024 |
Clinical Pharmacology and Pharmacogenomics[...] |
Article |
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2.
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While therapeutic drug monitoring is a potentially attractive strategy that can be utilized by clinical pharmacologists to optimize drug dosing, the costs and risks must [...]
11 April 2024 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Article |
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3.
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Variation in gene expression has been observed in natural populations and associated with complex traits or phenotypes such as disease susceptibility and drug response [...]
21 October 2010 |
Clinical Pharmacology and Pharmacogenomics; Human Genetics; Medicine; Public Health Sciences |
Article |
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4.
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Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitativ [...]
03 April 2014 |
Ben May Department for Cancer Research; Clinical Pharmacology and Pharmacogenomics; Genetics, Genomics, and Systems Biology; Human Genetics; Medicine |
Article |
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To reduce treatment of indolent prostate cancer (PCa), biomarkers are needed to improve identification of patients with a low-risk of having aggressive disease. Over-t [...]
14 April 2015 |
Clinical Pharmacology and Pharmacogenomics |
Article |
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The discovery of expression quantitative trait loci (“eQTLs”) can help to unravel genetic contributions to complex traits. We identified genetic determinants of hu [...]
26 May 2011 |
Clinical Pharmacology and Pharmacogenomics; Ecology and Evolution; Medicine |
Article |
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7.
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Belinostat is a hydroxamate class HDAC inhibitor that has demonstrated activity in peripheral T-cell lymphoma and is undergoing clinical trials for non-hematologic mal [...]
30 January 2013 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Article |
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8.
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Quaternary derivatives of noroxymorphone are used to prevent or relieve nausea and emesis associated with the use of narcotic analgesics without interfering with the anal [...]
29 August 1989 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Patent |
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9.
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Quaternary derivatives of noroxymorphone are used to prevent or relieve nausea and emesis associated with the use of narcotic analgesics without interfering with the anal [...]
12 January 1988 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Patent |
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10.
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UDP-glucuronosyltransferases 1A isoforms belong to a superfamily of microsomal enzymes responsible for glucuronidation of numerous endogenous and exogenous compounds. The [...]
25 April 2007 |
Ben May Department for Cancer Research; Clinical Pharmacology and Pharmacogenomics; Medicine |
Article |
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11.
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Background: Hospitalizations are a vital opportunity for the initiation of life-saving opioid agonist therapy (OAT) for patients with opioid use disorder. A novel appr [...]
01 June 2023 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Article |
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12.
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Purpose: Frequencies of single nucleotide polymorphisms (SNPs) from pain related candidate genes are available for individuals with sickle cell disease (SCD). One of t [...]
11 November 2019 |
Clinical Pharmacology and Pharmacogenomics |
Article |
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13.
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Immune checkpoint inhibitors (ICI) are the standard of care for various malignancies and have been associated with a wide spectrum of complications that are phenotypicall [...]
08 February 2023 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Article |
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