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1.
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Proteins are molecular machines and to understand how they work, we need to understand how they move. New pump-probe time-resolved X-ray diffraction methods open up ways [...]
15 April 2024 |
Biochemistry and Molecular Biology; Ecology and Evolution |
Article |
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2.
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Several physical mechanisms have been proposed to explain allostery in proteins. They differ by the number of internal states that they assume a protein to occupy, leavin [...]
09 November 2023 |
Biochemistry and Molecular Biology; Biophysical Sciences |
Article |
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3.
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<p>Epistatic interactions between mutations add substantial complexity to adaptive landscapes and are often thought of as detrimental to our ability to predict evol [...]
03 April 2023 |
Ecology and Evolution |
Article |
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4.
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The metabolic activity of microbial communities is central to their role in biogeochemical cycles, human health, and biotechnology. Despite the abundance of sequencing da [...]
19 December 2023 |
Biophysical Sciences; Ecology and Evolution; Physics |
Article |
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5.
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To achieve maximal growth, cells must manage a massive economy of ribosomal proteins (r-proteins) and RNAs (rRNAs) to produce thousands of ribosomes every minute. Althoug [...]
07 March 2019 |
Molecular Genetics and Cell Biology |
Article |
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6.
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Protein function arises from a poorly understood pattern of energetic interactions between amino acid residues. Sequence-based strategies for deducing this pattern have b [...]
19 July 2018 |
Biochemistry and Molecular Biology |
Article |
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7.
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The heat shock response (HSR) controls expression of molecular chaperones to maintain protein homeostasis. Previously, we proposed a feedback loop model of the HSR in whi [...]
09 May 2023 |
Genetics, Genomics, and Systems Biology; Molecular Genetics and Cell Biology |
Article |
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8.
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The ribosome translates the genetic code into proteins in all domains of life. Its size and complexity demand long-range interactions that regulate ribosome function. The [...]
03 August 2020 |
Biochemistry and Molecular Biology |
Article |
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9.
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Microbial community assembly is a complex dynamical process that determines community structure and function. The interdependence of inter-species interactions and nutrie [...]
26 May 2023 |
Ecology and Evolution |
Article |
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