The overall goal of research was to analyze magnetic resonance imaging (MRI) radiomic features extracted from the non-cystic kidney parenchyma of patients with autosomal dominant polycystic kidney disease (ADPKD) for genotype and risk-stratified classification, temporal assessment of radiomic features for the prediction of kidney function decline, and the analysis of radiomic-based differences from magnetic resonance fingerprinting (MRF)-acquired T1 and T2 maps between a healthy control and an ADPKD cohort.