Cell permeable peptides derived from MLL that block the interaction of MLL with menin for the treatment of acute myeloid and acute lymphoid leukemia are disclosed. Small molecules interfere with the interaction of MLL with any of its binding partners.
Details
Title
Therapeutics to inhibit MLL-menin interaction for treating leukemia
Inventors
Thirman, Michael J. : University of Chicago
Applicants
Thirman, Michael J. University of Chicago