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1.
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<p>Background: Adverse childhood experiences (ACE) are important predictors of mental health outcomes in adulthood. However, commonly used ACE measures such as the [...]
16 April 2024 |
Medicine |
Article |
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2.
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Cells must sense and respond to sudden maladaptive environmental changes—stresses—to survive and thrive. Across eukaryotes, stresses such as heat shock trigger conser [...]
11 April 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences; Genetics, Genomics, and Systems Biology; Medicine |
Article |
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3.
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While therapeutic drug monitoring is a potentially attractive strategy that can be utilized by clinical pharmacologists to optimize drug dosing, the costs and risks must [...]
11 April 2024 |
Clinical Pharmacology and Pharmacogenomics; Medicine |
Article |
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4.
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No abstract
12 April 2024 |
Medicine; Surgery |
Article |
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5.
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Despite the recognized gut-brain axis link, natural variations in microbial profiles between patients hinder definition of normal abundance ranges, confounding the impact [...]
10 April 2024 |
Genetics, Genomics, and Systems Biology; Medicine; Pediatrics; Quantitative Methods in Social, Behavioral, and Health Sciences |
Article |
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6.
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Bacillus Calmette–Guérin (BCG) vaccination induces memory characteristics in innate immune cells and their progenitors, a process called trained immunity mediated by e [...]
11 March 2024 |
Immunology; Medicine |
Article |
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7.
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People who nonmedically use drugs (PWUD) face intricate social issues that suppress self-actualization, communal integration, and overall health and wellness. “Strength [...]
08 April 2024 |
Medicine |
Article |
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8.
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It is well known that dietary choices impact both individual and global health. However, there are numerous challenges at the personal and systemic level to fostering sus [...]
27 March 2024 |
Medicine; Public Health Sciences |
Article |
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9.
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Humans exhibit considerable variability in their immune responses to the same immune challenges. Such variation is widespread and affects individual and population-level [...]
05 April 2024 |
Genetics, Genomics, and Systems Biology; Human Genetics; Immunology; Medicine |
Article |
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10.
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<p>Background: In recent years, stimulant use has increased among persons who use opioids in the rural U.S., leading to high rates of overdose and death. We sought [...]
01 April 2024 |
Medicine |
Article |
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11.
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<p>Background: Objective tools to define the optimal time for referral for advanced therapies and to help guide escalation and de-escalation of support can improve [...]
04 March 2024 |
Medicine |
Article |
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12.
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Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software e [...]
27 March 2024 |
Computer Science; Medicine |
Article |
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13.
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Biopolymer translocation is a key step in viral infection processes. The transfer of information-encoding genomes allows viruses to reprogram the cell fate of their hosts [...]
01 May 2018 |
Medicine |
Article |
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14.
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<p>Importance: Arginine deprivation using ADI-PEG20 (pegargiminase) combined with chemotherapy is untested in a randomized study among patients with cancer. ATOMIC- [...]
15 February 2024 |
Medicine |
Article |
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15.
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No abstract
28 February 2024 |
Medicine; Pediatrics; Psychiatry and Behavioral Neuroscience |
Article |
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16.
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Previously, we showed that a massively parallel reporter assay, mSTARR-seq, could be used to simultaneously test for both enhancer-like activity and DNA methylation-depen [...]
26 February 2024 |
Human Genetics; Immunology; Medicine |
Article |
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17.
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Automated algorithms for identifying potential pre-exposure prophylaxis (PrEP) candidates are effective among men, yet often fail to detect cisgender women (hereafter ref [...]
14 March 2024 |
Medicine |
Article |
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18.
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Plasmids are extrachromosomal genetic elements that often encode fitness-enhancing features. However, many bacteria carry “cryptic” plasmids that do not confer clear [...]
29 February 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences; Medicine; Microbiology |
Article |
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19.
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No abstract
08 March 2024 |
Medicine |
Article |
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20.
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<p>Importance: Suicide has been a leading manner of death for US Air Force personnel in recent years. Universal prevention programs that reduce suicidal thoughts an [...]
21 October 2020 |
Medicine; Public Health Sciences |
Article |
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21.
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No abstract
28 February 2024 |
Medicine |
Article |
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22.
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No abstract
12 April 2021 |
Medicine; Pathology |
Article |
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23.
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<p>Importance: Short sleep duration has been recognized as a risk factor for obesity. Whether extending sleep duration may mitigate this risk remains unknown.</p [...]
07 February 2022 |
Medicine; Public Health Sciences |
Article |
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24.
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<p>Importance: Given conflicting results regarding the prognosis of erb-b2 receptor tyrosine kinase 2 (ERBB2; formerly HER2 or HER2/neu)–low breast cancer, a larg [...]
23 February 2023 |
Medicine; Public Health Sciences |
Article |
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25.
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No abstract
02 April 2021 |
Medicine; Public Health Sciences |
Article |
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