The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve coagulase Domains 1-2 and variants thereof.
Details
Title
Staphylococcal coagulase antigens and methods of their use
Inventors
McAdow, Molly : University of Chicago Dedent, Andrea : University of Chicago Cheng, Alice : University of Chicago Emolo, Carla : University of Chicago Missiakas, Dominique : University of Chicago Schneewind, Olaf : University of Chicago