The present disclosure provides combinations of immunologic inhibitors for the treatment of cancer. In some embodiments, the methods involve the use of a combination of at least two of the following: an inhibitor of indoleamine-2,3-dioxygenase (IDO), an inhibitor of the PD-L1/PD-1 pathway, an inhibitor of CTLA-4, an inhibitor of CD25, or IL-7.
Details
Title
Synergistic combination of immunologic inhibitors for the treatment of cancer
Inventors
Gajewski, Thomas F. : University of Chicago Spranger, Stefani : University of Chicago Leung, Michael : University of Chicago