Tissue-resident memory T cells in immune-related adverse events: Friend or foe?
Reschke, Robin; Gajewski, Thomas F.
2023

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Abstract

Many cancer patients experience toxicity during checkpoint blockade immunotherapy, which often leads to treatment discontinuation. To this end, understanding the mechanisms mediating immune-related adverse events (irAE) should ultimately enable improvement in clinical outcomes. Recent work has revealed that tissue-resident memory T (TRM) cells are locally expanded in irAE-dermatitis and -colitis.

Details

Title
Tissue-resident memory T cells in immune-related adverse events: Friend or foe?
Author
Reschke, Robin : University of Chicago
Gajewski, Thomas F. : University of Chicago
Content Type
Article
Published in
OncoImmunology
Keywords
Identifier(s)
DOI: https://doi.org/10.1080/2162402X.2023.2197358
Funding Information
German Research Foundation, DFG RE 4468/2-1
Publication Date
2023-04-04
Language
English
Copyright Statement

© 2023 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Record Appears in
Biological Sciences Division > Pathology
Biological Sciences Division > Medicine
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Record Created
2023-04-11

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