Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier

Bandyopadhyay, Esha : University of Chicago : (https://orcid.org/0000-0002-8080-2825)
Witonsky, David : University of Chicago
de la Fuente Castro, Constanza : University of Chicago : (https://orcid.org/0000-0002-2857-3615)
Pasupuleti, Nagarjuna : Birbal Sahni Institute of Palaeosciences : (https://orcid.org/0000-0002-1886-4400)
Urban Aragon, Jose A. : University of Chicago : (https://orcid.org/0000-0002-2350-2244)
Lee, Juhyeon : Seoul National University : (https://orcid.org/0000-0001-7008-4471)
Shastry, Vivaswat : University of Chicago : (https://orcid.org/0000-0002-7294-5607)
Sander, Nathan : University of Chicago
Ahlawat, Bhavna : Birbal Sahni Institute of Palaeosciences : (https://orcid.org/0000-0003-2095-0532)
Dwivedi, Aparna : Birbal Sahni Institute of Palaeosciences : (https://orcid.org/0009-0004-6267-9810)
Angmo, Tanzin : Rock Art and Historical Society of Spiti
Sharma, Aman : Shoolini University : (https://orcid.org/0009-0001-6986-745X)
Kaushik, Amit : Chaudhary Charan Singh Haryana Agricultural University : (https://orcid.org/0000-0001-8742-5404)
Moots, Hannah Marie : University of Chicago : (https://orcid.org/0000-0002-6637-6321)
Moreno-Mayar, J. Víctor : University of Copenhagen : (https://orcid.org/0000-0002-7712-4496)
Kumar, Sachin : Birbal Sahni Institute of Palaeosciences : (https://orcid.org/0000-0002-5249-305X)
Bhatt, Rakesh Chandra : Hemwati Nandan Bahuguna Garhwal University : (https://orcid.org/0000-0002-5738-1487)
Mengwal, Kavita Bist : Archaeological Survey of India : (https://orcid.org/0009-0008-0492-1292)
Chauhan, Hari : Himachal State Museum
Ganjoo, Rajinder K. : University of Jammu : (https://orcid.org/0000-0001-6256-2314)
Mushrif-Tripathy, Veena : Deccan College Post Graduate and Research Institute
Ota, Simadri Bihari : Archaeological Survey of India
Warinner, Christina : Harvard University : (https://orcid.org/0000-0002-4528-5877)
Aldenderfer, Mark : University of California : (https://orcid.org/0000-0002-7033-4319)
Di Rienzo, Anna : University of Chicago : (https://orcid.org/0000-0002-8982-9098)
Jeong, Choongwon : Seoul National University : (https://orcid.org/0000-0003-3049-2352)
Rawat, Nagendra Singh : Hemwati Nandan Bahuguna Garhwal University : (https://orcid.org/0000-0001-7833-0382)
Norbu, Tsering : Rock Art and Historical Society of Spiti
Singh, Ekta : Shoolini University : (https://orcid.org/0000-0002-5572-2524)
Nautiyal, Vinod : Hemwati Nandan Bahuguna Garhwal University
Raghavan, Maanasa : University of Chicago : (https://orcid.org/0000-0003-1997-0739)
Rai, Niraj : Birbal Sahni Institute of Palaeosciences : (https://orcid.org/0000-0002-1251-9390)

Article

Science Advances

DOI: https://doi.org/10.1126/sciadv.adu9625

Raw data (fastq files) and alignments (bam files) for the ancient individuals sequenced in this study are available through the Sequence Read Archive (SRA) BioProject accession number PRJNA1250143. In compliance with the informed consent associated with the present-day individuals who participated in the study, raw data (fastq files) and alignments (bam files) are available for demographic analyses through the European Genome-phenome Archive (EGA) accession number EGAS50000001342, under data access agreement with the corresponding authors M.R. (mraghavan@uchicago.edu) and N.R. (nirajrai@bsip.res.in) and an independent (nonauthor) contact, K. Thangaraj (thangs@ccmb.res.in). All data needed to evaluate the conclusions in the paper are present in the paper and/or the Supplementary Materials. The remaining datasets listed in the “Data compilation” section that were not generated in this study can be accessed through public data repositories or data access agreements, as noted in the respective publications.

National Institutes of Health, (https://ror.org/01cwqze88), ROR, R35GM143094
National Institutes of Health, (https://ror.org/01cwqze88), ROR, R01HL1195077-08
European Molecular Biology Organization, (https://ror.org/04wfr2810), ROR, EMBO-STF-8028
University of Chicago, (https://ror.org/024mw5h28), ROR
Villum Fonden, (https://ror.org/05nqkay65), ROR, VIL53099
European Research Council, (https://ror.org/0472cxd90), ROR, 101078151
Birbal Sahni Institute of Palaeosciences, (https://ror.org/05xc5re08), ROR

2025-10-31

English

© 2025 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

Biological Sciences Division > Genetics, Genomics, and Systems Biology
Biological Sciences Division > Human Genetics
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2025-11-03