Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling.
Details
Title
Compositions and methods for activating NRF2-dependent gene expression
Inventors
Moellering, Raymond : University of Chicago Coukos, John : University of Chicago Lee, Gihoon : University of Chicago Chang, Jae Won : University of Chicago Mutlu, Gokhan : University of Chicago