1.
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A fundamental problem in computer simulation of systems of biophysical interest is the separation of timescales. This refers to the fact that stable integration of the e [...]
2024-03 |
Chemistry |
Dissertation |
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2.
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The selective activation and functionalization of C–H bonds is a major challenge in synthetic chemistry. Transition metal-oxo complexes are particularly adept at accomp [...]
2024-03 |
Chemistry |
Dissertation |
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3.
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First-principles studies, grounded in quantum mechanics, offer a profound understanding of materials and chemical systems at the most fundamental level without relying on [...]
2024-03 |
Chemistry |
Dissertation |
|
4.
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Protein design has emerged as an important field in contemporary biology, driven in part by the accumulation of vast amounts of protein data in public databases like the [...]
2024-03 |
Chemistry |
Dissertation |
|
5.
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The study of epigenetics, particularly DNA methylation, provides crucial insights into gene regulation and its aberrations in diseases such as cancer. This dissertation i [...]
2024-03 |
Chemistry |
Dissertation |
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6.
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A complex set of cellular processes regulates the binding of peripheral membrane proteins to lipid membranes to allow for intercellular communication and function. Two me [...]
2024-03 |
Chemistry |
Dissertation |
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7.
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Biointerface is the area where a biological entity interacts with a biomaterial. Properly designing a biointerface enhances the functionalities of biomaterials in recordi [...]
2024-03 |
Chemistry |
Dissertation |
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8.
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Bioelectronics are bio-interfacing devices that can be used for interrogating fundamental biological mechanisms and performing electronic diagnosis and therapy. A variety [...]
2024-03 |
Chemistry |
Dissertation |
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9.
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The development of general methods for the organization of molecules on technologically relevant materials enables the exploration of properties and functions that are no [...]
2024-03 |
Chemistry |
Dissertation |
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10.
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2-Thiouridine (s<sup>2</sup>U) is a nucleobase modification that confers enhanced efficiency and fidelity both on modern tRNA codon translation and on nonenzy [...]
31 January 2024 |
Chemistry |
Article |
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11.
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Chemoradiotherapy combines radiotherapy with concurrent chemotherapy to potentiate antitumor activity but exacerbates toxicities and causes debilitating side effects in c [...]
21 February 2024 |
Chemistry; Radiation and Cellular Oncology |
Article |
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12.
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The epitranscriptomics field has undergone tremendous growth since the discovery that the RNA <em>N</em><sup>6</sup>-methyladenosine (m<sup> [...]
15 December 2023 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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13.
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System specific neural force fields (NFFs) have gained popularity in computational chemistry. One of the most popular datasets as a bencharmk to develop NFF models is the [...]
20 February 2024 |
Chemistry; Computer Science; Kadanoff Center for Theoretical Physics |
Article |
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14.
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Methods for forming samples of noble metal bipyramid nanocrystals having very low size and shape polydispersities from samples of mixed noble metal nanocrystals are provi [...]
16 January 2024 |
Chemistry |
Patent |
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15.
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This mini review examines the current advances and future prospects of chemical approaches in deformable bioelectronics, emphasizing their transformative potential in hea [...]
30 August 2023 |
Chemistry |
Article |
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16.
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The complexity of eukaryotic organisms is intricately tied to transcriptome-level processes, notably alternative splicing and the precise modulation of gene expression th [...]
16 February 2024 |
Chemistry |
Article |
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17.
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Lysosomal calcium (Ca<sup>2+</sup>) release is critical to cell signaling and is mediated by well-known lysosomal Ca<sup>2+</sup> channels. Yet, h [...]
14 February 2024 |
Chemistry |
Article |
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18.
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The Ciona intestinalis voltage-sensing phosphatase (Ci-VSP) is a membrane protein containing a voltage-sensing domain (VSD) that is homologous to VSDs from voltage-gated [...]
15 February 2024 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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19.
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Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials [...]
03 January 2024 |
Chemistry |
Article |
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20.
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The ability to seamlessly merge electronic devices with biological systems at the cellular length scale is an exciting prospect for exploring new fundamental cell biology [...]
16 December 2016 |
Chemistry |
Article |
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21.
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R-loops affect transcription and genome stability. Dysregulation of R-loops is related to human diseases. Genome-wide R-loop mapping typically uses the S9.6 antibody or i [...]
30 November 2022 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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22.
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N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) is one of the most abundant messenger RNA modifications in eukaryotes involved in various pivotal p [...]
03 June 2019 |
Biochemistry and Molecular Biology; Chemistry |
Article |
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23.
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Measuring the behavior of redox-active molecules in space and time is crucial for understanding chemical and biological systems and for developing new technologies. Optic [...]
08 November 2019 |
Chemistry |
Article |
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24.
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Inositol hexakisphosphates (IP<sub>6</sub>) are cellular cofactors that promote the assembly of mature capsids of HIV. These negatively charged molecules coor [...]
16 September 2020 |
Chemistry |
Article |
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25.
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E3 ubiquitin (UB) ligases E4B and carboxyl terminus of Hsc70-interacting protein (CHIP) use a common U-box motif to transfer UB from E1 and E2 enzymes to their substrate [...]
03 January 2018 |
Chemistry |
Article |
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