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1.	Multiple Files sciadv.ade1942 A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans Gray, Olivia A. ; Yoo, Jennifer ; Sobreira, Débora R. ; Jousma, Jordan ; Witonsky, David ; Sak[...] In Tibetans, noncoding alleles in EPAS1—whose protein product hypoxia-inducible factor 2α (HIF-2α) drives the response to hypoxia—carry strong signatures of positiv [...] 23 November 2022 \| Human Genetics; Medicine \| Article \| Detailed record - Similar records
2.	Multiple Files Dynamin-related-protein-1 Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury Piao, Lin ; Fang, Yong-Hu ; Fisher, Michael ; Hamanaka, Robert B. ; Ousta, Alaa ; Wu, Rongxu ; Mut[...] Dynamin-related protein 1 (Drp1) is a cytosolic GTPase protein that when activated translocates to the mitochondria, meditating mitochondrial fission and increasing react [...] 22 December 2023 \| Medicine \| Article \| Detailed record - Similar records
3.	Multiple Files elife-25217-v2 <i>HIF-1α</i> is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium Wu, David ; Huang, Ru-Ting ; Hamanaka, Robert B. ; Krause, Matt ; Oh, Myung-Jin ; Kuo, Cheng-Hs[...] Hemodynamic forces regulate vascular functions. Disturbed flow (DF) occurs in arterial bifurcations and curvatures, activates endothelial cells (ECs), and results in vasc [...] 30 May 2017 \| Medicine \| Article \| Detailed record - Similar records
4.	PDF elife-27563-v1 Chemoreception: Keeping carbon dioxide in check Garcia, Alfredo J. ; Ramirez, Jan-Marino No abstract 17 May 2017 \| Medicine \| Article \| Detailed record - Similar records
5.	PDF journal.pone.0075838 Xanthine Oxidase Mediates Hypoxia-Inducible Factor-2α Degradation by Intermittent Hypoxia Nanduri, Jayasri ; Vaddi, Damodara Reddy ; Khan, Shakil A. ; Wang, Ning ; Makerenko, Vladisl[...] <p>Sleep-disordered breathing with recurrent apnea produces chronic intermittent hypoxia (IH). We previously reported that IH leads to down-regulation of HIF-2α pr [...] 04 October 2013 \| Institute for Integrative Physiology; Center for Systems Biology of Oxygen Sensing \| Article \| Detailed record - Similar records
6.	PDF journal.pone.0119762 HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase Nanduri, Jayasri ; Vaddi, Damodara Reddy ; Khan, Shakil A. ; Wang, Ning ; Makerenko, Vladisl[...] <p>Hypoxia-inducible factor 1 (HIF-1) mediates many of the systemic and cellular responses to intermittent hypoxia (IH), which is an experimental model that simulat [...] 09 March 2015 \| Center for Systems Biology of Oxygen Sensing; Institute for Integrative Physiology \| Article \| Detailed record - Similar records
7.	PDF Vascular-pathophysiology-in-hypoxia Editorial: Vascular pathophysiology in hypoxia Das, Kusal K. ; Majid, Dewan S. A. ; Prabhakar, Nanduri R. No abstract 07 July 2023 \| Medicine \| Article \| Detailed record - Similar records
8.	Multiple Files Hypoxia-sensing-requires-H2S-dependent-persulfidation-of-olfactory-receptor-78 Hypoxia sensing requires H<sub>2</sub>S-dependent persulfidation of olfactory receptor 78 Jie Peng, Ying-Jie ; Nanduri, Jayasri ; Wang, Ning ; Kumar, Ganesh K. ; Bindokas, Vytautas ; Pa[...] Oxygen (O<sub>2</sub>) sensing by the carotid body is critical for maintaining cardiorespiratory homeostasis during hypoxia. Hydrogen sulfide (H<sub>2&l [...] 07 July 2023 \| Pharmacological and Physiological Sciences \| Article \| Detailed record - Similar records
9.	Multiple Files Consequence-of-immature-breathing-induces-persistent-changes-in-hippocampal-synaptic-plasticity-and-behavior A consequence of immature breathing induces persistent changes in hippocampal synaptic plasticity and behavior: A role of prooxidant state and NM[...] Arias-Cavieres, Alejandra ; Garcia, Alfredo J., III Underdeveloped breathing results from premature birth and causes intermittent hypoxia during the early neonatal period. Neonatal intermittent hypoxia (nIH) is a condition [...] 29 June 2023 \| Medicine \| Article \| Detailed record - Similar records
10.	Multiple Files journal.pone.0215905 Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells Vaddi, Damodara Reddy ; Piao, Lin ; Khan, Shakil A. ; Wang, Ning ; Prabhakar, Nanduri R. ; Nand[...] The alpha subunit of the voltage gated human ether-a-go-go-related (hERG) potassium channel regulates cell excitability in a broad range of cell lines. HERG channels are [...] 24 April 2019 \| Center for Systems Biology of Oxygen Sensing; Institute for Integrative Physiology \| Article \| Detailed record - Similar records
11.	Multiple Files Carotid-body-hypersensitivity-in-intermittent-hypoxia-and-obtructive-sleep-apnoea Carotid body hypersensitivity in intermittent hypoxia and obtructive sleep apnoea Prabhakar, Nanduri R. ; Peng, Ying-Jie ; Nanduri, Jayasri Carotid bodies are the principal sensory organs for detecting changes in arterial blood oxygen concentration, and the carotid body chemoreflex is a major regulator of the [...] 07 April 2023 \| Center for Systems Biology of Oxygen Sensing; Institute for Integrative Physiology \| Article \| Detailed record - Similar records
12.	PDF Rapid-emergence-from-dexmedetomidine-sedation-in-Sprague-Dawley-rats Rapid emergence from dexmedetomidine sedation in Sprague Dawley rats by repurposing an α<sub>2</sub>-adrenergic receptor competitive antagonist i[...] Xie, Zheng ; Fox, Aaron P. <p>Background: The α2 adrenergic receptor agonist dexmedetomidine is an important intravenous sedative with analgesic properties. Currently available dexmedetomidi [...] 01 February 2023 \| Anesthesia and Critical Care; Neurobiology; Pharmacological and Physiological Sciences \| Article \| Detailed record - Similar records
13.	Multiple Files Gasotransmitter-modulation-of-hypoglossal-motoneuron-activity Gasotransmitter modulation of hypoglossal motoneuron activity Browe, Brigitte M. ; Peng, Ying-Jie ; Nanduri, Jayasri ; Prabhakar, Nanduri R. ; Garcia, Alf[...] Obstructive sleep apnea (OSA) is characterized by sporadic collapse of the upper airway leading to periodic disruptions in breathing. Upper airway patency is governed by [...] 19 January 2023 \| Medicine \| Article \| Detailed record - Similar records

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