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Plasmids are extrachromosomal genetic elements that often encode fitness-enhancing features. However, many bacteria carry “cryptic” plasmids that do not confer clear [...]
29 February 2024 |
Biochemistry and Molecular Biology; Biophysical Sciences; Medicine; Microbiology |
Article |
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<p>Bile acids (BAs) are cholesterol-derived molecules that aid in digestion and nutrient absorption, regulate host metabolic processes, and influence physiology of [...]
04 January 2024 |
Medicine |
Article |
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3.
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It is well-established that women are disproportionately affected by Alzheimer’s disease. The mechanisms underlying this sex-specific disparity are not fully understood [...]
21 January 2024 |
Neurobiology; Obstetrics and Gynecology |
Article |
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4.
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Disparate redox activities that take place beyond the bounds of the prokaryotic cell cytosol must connect to membrane or cytosolic electron pools. Proteins post-translati [...]
25 May 2021 |
Microbiology |
Article |
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Cellular respiration is essential for multiple bacterial pathogens and a validated antibiotic target. In addition to driving oxidative phosphorylation, bacterial respirat [...]
05 April 2022 |
Microbiology |
Article |
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Cellular behaviors emerge from layers of molecular interactions: proteins interact to form complexes, pathways, and phenotypes. We show that hierarchical networks of prot [...]
17 August 2022 |
Pathology |
Article |
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7.
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<p>Gram-negative pathogens, such as Klebsiella pneumoniae, remodel their outer membrane (OM) in response to stress to maintain its integrity as an effective barrier [...]
08 February 2021 |
Medicine; Microbiology |
Article |
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8.
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Maternal immune activation (MIA) derived from late gestational infection such as seen in chorioamnionitis poses a significantly increased risk for neurodevelopmental defi [...]
17 February 2023 |
Pediatrics; Radiology |
Article |
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9.
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The microbiome modulates host immunity and aids the maintenance of tolerance in the gut, where microbial and food-derived antigens are abundant. Yet modern dietary factor [...]
22 December 2022 |
Cancer Biology; Chemistry; Immunology; Microbiology; Pathology; Pediatrics |
Article |
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10.
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Respiratory failure and mortality from COVID-19 result from virus- and inflammation-induced lung tissue damage. The intestinal microbiome and associated metabolites are i [...]
03 November 2022 |
Medicine; Public Health Sciences |
Article |
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