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1.
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In Tibetans, noncoding alleles in EPAS1—whose protein product hypoxia-inducible factor 2α (HIF-2α) drives the response to hypoxia—carry strong signatures of positive sele [...]
23 November 2022 |
Human Genetics[...] |
Article |
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2.
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Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditio [...]
23 June 2020 |
Medicine; Neurobiology |
Patent |
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3.
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Sleep-disordered breathing with recurrent apnea produces chronic intermittent hypoxia (IH). We previously reported that IH leads to down-regulation of HIF-2α protein v [...]
04 October 2013 |
Institute for Integrative Physiology[...] |
Article |
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4.
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Hypoxia-inducible factor 1 (HIF-1) mediates many of the systemic and cellular responses to intermittent hypoxia (IH), which is an experimental model that simulates O
09 March 2015 |
Center for Systems Biology of Oxygen Sensing[...] |
Article |
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5.
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Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditio [...]
23 May 2013 |
Medicine[...] |
Patent |
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6.
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No abstract
07 July 2023 |
Medicine |
Article |
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7.
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Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditio [...]
23 May 2013 |
Neurobiology; Medicine |
Patent |
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8.
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The alpha subunit of the voltage gated human ether-a-go-go-related (hERG) potassium channel regulates cell excitability in a broad range of cell lines. HERG channels are [...]
24 April 2019 |
Center for Systems Biology of Oxygen Sensing[...] |
Article |
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9.
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Carotid bodies are the principal sensory organs for detecting changes in arterial blood oxygen concentration, and the carotid body chemoreflex is a major regulator of the [...]
07 April 2023 |
Center for Systems Biology of Oxygen Sensing[...] |
Article |
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