Center for Systems Biology of Oxygen Sensing

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Center for Systems Biology of Oxygen Sensing 9 records found Search took 0.11 seconds. 
1.
In Tibetans, noncoding alleles in EPAS1—whose protein product hypoxia-inducible factor 2α (HIF-2α) drives the response to hypoxia—carry strong signatures of positiv [...]
23 November 2022 | Human Genetics; Medicine | Article |
2.
Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditio [...]
23 June 2020 | Medicine; Neurobiology | Patent |
3.

Sleep-disordered breathing with recurrent apnea produces chronic intermittent hypoxia (IH). We previously reported that IH leads to down-regulation of HIF-2α protein [...]

04 October 2013 | Institute for Integrative Physiology; Center for Systems Biology of Oxygen Sensing | Article |
4.

Hypoxia-inducible factor 1 (HIF-1) mediates many of the systemic and cellular responses to intermittent hypoxia (IH), which is an experimental model that simulates O 09 March 2015 | Center for Systems Biology of Oxygen Sensing; Institute for Integrative Physiology | Article |

5.
Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditio [...]
23 May 2013 | Medicine; Neurobiology | Patent |
6.
7.
Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditio [...]
23 May 2013 | Neurobiology; Medicine | Patent |
8.
The alpha subunit of the voltage gated human ether-a-go-go-related (hERG) potassium channel regulates cell excitability in a broad range of cell lines. HERG channels are [...]
24 April 2019 | Center for Systems Biology of Oxygen Sensing; Institute for Integrative Physiology | Article |
9.
Carotid bodies are the principal sensory organs for detecting changes in arterial blood oxygen concentration, and the carotid body chemoreflex is a major regulator of the [...]
07 April 2023 | Center for Systems Biology of Oxygen Sensing; Institute for Integrative Physiology | Article |

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