A method for preventing or treating opioid induced changes in gastrointestinal motility. The method comprises administering methylnaltrexone or another quaternary derivative of noroxymorphone to a patient prior to the administration of an opioid or after the onset of side effects induced by the administration of an opioid, wherein the methylnaltrexone or quaternary derivative is administered orally in an enterically coated form.
Details
Title
Use of methylnaltrexone and related compounds
Inventors
Foss, Joseph F. : University of Chicago Roizen, Michael F. : University of Chicago Moss, Jonathan : University of Chicago Yuan, Chun-Su : University of Chicago Drell, William : University of Chicago
Applicants
University of Chicago U R Labs
Content Type
Patent
Assignees
Progenics Pharmaceuticals Nevada Inc. University of Chicago
