A method of preventing or treating constipation in a patient who has been chronically taking opioids, the method comprising administering a quaternary derivative of noroxymorphone in an amount sufficient to prevent or treat the side effect in the patient, but which amount would be insufficient to treat a patient with the same opioid-induced side effect who had not chronically been administered opioids.
Details
Title
USE OF METHYLNALTREXONE AND RELATED COMPOUNDS TO TREAT CONSTIPATION IN CHRONIC OPIOID USERS
Inventors
Foss, Joseph F. : University of Chicago Roizen, Michael F. : University of Chicago Moss, Jonathan : University of Chicago Yuan, Chun-Su : University of Chicago Drell, William : University of Chicago
Applicants
Foss, Joseph F. Roizen, Michael F. Moss, Jonathan Yuan, Chun-Su Drell, William University of Chicago
