The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
Details
Title
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
Inventors
Moss, Jonathan : University of Chicago Lingen, Mark : University of Chicago Singleton, Patrick A. : University of Chicago Garcia, Joe G. N. : University of Chicago Yuan, Chun-Su : University of Chicago