The Anti-Drug Abuse Acts of 1986 and 1988 led to a rapid increase in the number of incarcerated Americans. The rate of female incarceration has risen at a particularly high rate over the past 20 years. This article discusses the evolution of drug sentencing policy since 1986. It looks at characteristics of incarcerated women in order to understand how drug policy has influenced this population. The way women participate in the drug trade interacts with minimum sentencing laws to contribute to the rise in female incarceration. The article concludes with policy recommendations for a more equitable drug sentencing system.