The COVID-19 pandemic has resulted in vast and prolonged challenges to all aspects of life including individual, social, economic, and business activities. Following a year of mandatory closures and quarantine, organizational management are required to shift focus to remote working and care for employees in response to the COVID-19 pandemic. This study examines the impacts of the COVID-19 pandemic on employees from a multidisciplinary approach to Human Capital Management (HCM). After collecting qualitative data from employees in the Departments of Human Resources, this study examines questions of 1) how do Human Resources professionals perceive to be the changing mode of Human Capital Management because of the pandemic; 2) how do organizational support and regulations play a role in the process of transformation; and 3) what are future directions of the transformation organizations can adopt to optimize their Human Capital. The results showed the importance of investing in talents for organizations' long-term success in the aspects of Work From Home Adaptation, Cooperative-level Coping mechanisms, and future directions for HCM. 5 Future directions of improvement for organizations' long-term success are: 1) creating guidelines on remote working to minimize potential isolation, 2) elevating employees’ overall performance through up-skill and re-skill training, 3) utilizing employees’ work satisfaction to increase productivity, 4) providing more mental health-related support, and 5) providing flexibility for employees.