Published March 17, 2016
| Version v1
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METHODS AND COMPOSITIONS FOR INHIBITING HUMAN COPPER TRAFFICKING PROTEINS ATOX1 AND CCS
Creators
- 1. University of Chicago
Contributors
Patent applicants:
Description
Compositions and methods concern organic molecules that bind to human Atox1 and CCS at the copper trafficking interface of these proteins. This binding suppresses copper trafficking, which leads to inhibition of cancer cell proliferation and tumor growth. In addition to serving as an effective treatment of cancer, these organic molecules inhibit cellular copper uptake and can be used as treatment of disorders of copper metabolism such as Wilson's disease, which is characterized by copper overload, as well as wound healing.
Files
US20160074373.pdf
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Additional details
Identifiers
- Patent application number
- US 201414762980 A
- Patent number
- US 2016/0074373 A1
- Other
- oai:uchicago.tind.io:9470
Dates
- Patent filed
-
2014-01-23