Published September 28, 2021
| Version v1
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Method for highly sensitive DNA methylation analysis
Creators
- 1. University of Chicago
Contributors
Patent applicant:
Description
Methods, compositions and kits are provided to amplify the amount of genomic methylated DNA can by subsequently analyzed and/or sequenced. It has particular use with small amounts of DNA, including, but not limited to cell free DNA samples. In some embodiments, the ratio of polymerase and methyltransferase is controlled in order to provide maximum yields. In some embodiments, a dual primase/polymerase is used.
Files
US11130991.pdf
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Additional details
Identifiers
- Patent number
- US 11130991 B2
- Patent application number
- US 201816491278 A
- Other
- oai:uchicago.tind.io:7360
Dates
- Patent filed
-
2018-03-08