Published February 9, 2021 | Version v1
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Methods and compositions involving RAD51 inhibitors

Description

The present invention concerns methods and compositions involving inhibitors and of RAD51, a protein involved in homologous recombination. In some embodiments, there are methods for sensitizing cells to the effects of DNA damaging agents, which can have particular applications for cancer patients. In some embodiments of the invention, the RAD51 inhibitor is a small molecule that directly affects RAD51 activity, such as its ability to promote filament formation.

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US_10912761_B2.pdf

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Additional details

Identifiers

Patent number
US 10912761 B2
Patent application number
201314648115
Other
oai:uchicago.tind.io:9736

Dates

Patent filed
2013-11-27

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Radiation and Cellular Oncology