Published May 21, 2020
| Version v1
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Phospholipid Analogues
Creators
- 1. University of Chicago
- 2. Karl-Franzens-Universität
Contributors
Patent applicants:
Description
The present invention relates to a compound having a structure according to formula (I) or a salt thereof, wherein: R 1 is a branched or linear alkyl, acyl, alkenyl, hydroxyalkyl, hydroxyalkenyl, or hydroxy-alkinyl residue comprising 6 to 30 carbon atoms, R 2 is selected from the group consisting of: a) an alkyl residue comprising 1 to 10 carbon atoms and comprising a terminal or cyclic quaternary ammonium, b) an alkyl residue comprising 1 to 10 carbon atoms and comprising a terminal amino group and/or 1 to 3 hydroxyl groups, c) an amino acid residue, d) a five or six carbon sugar and e) H, R 3 is a residue selected from the group consisting of an alkyl, alkenyl, prostanyl-dialkyl, furanyl-dialkyl, cyclobutyl-dialkyl, cycloalkyl and aryl group of 2 to 40 carbon atoms length and comprising at least one keto group, epoxy group, aldehyde group, peroxy group, hydroperoxy group, hydroxyl group or a free carboxyl group, L 1 is selected from the group consisting of O, NH, S, CH 2 , (aa), (bb), (cc), (dd), (ee), (ff), (gg), (hh), (ii), (jj), (kk), (ll), (mm), or (nn), L2 is an amide group or an ether group, X and Z are independently O, S or CH 2 , and Y is selected from the group consisting of O and S.
Files
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Additional details
Identifiers
- Patent application number
- US 201816635883 A
- Patent number
- US 2020/0157127 A1
- Other
- oai:uchicago.tind.io:7993
Dates
- Patent filed
-
2018-07-27