Pritzker School of Molecular Engineering
Published January 4, 2022 | Version v1
Patent Open

System and method for en masse patterning of molecule structures

Creators

  • 1. University of Wisconsin-Madson
  • 2. University of Wisconsin-Madison
  • 3. University of Chicago
  • 4. Leiden University

Contributors

Description

Devices, systems, and methods for en masse patterning of nucleic acid molecule structures are disclosed. The devices can include microchannels and nanoslits. The microchannels and nanoslits can be connected by parking chambers. The systems and methods can utilize the geometry of the devices in coordination with a voltage application routine to park nucleic acid molecules in the parking chambers and subsequently inject the nucleic acid molecules into the nanoslits. The methods can be utilized to present nucleic acid molecules in a fashion suitable for genomic analysis. The methods can also be utilized to provide size selection of the nucleic acid molecules.

Files

US11213825.pdf

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Additional details

Identifiers

Patent number
US 11213825 B2
Patent application number
US 201816614003 A
Other
oai:uchicago.tind.io:7413

Dates

Patent filed
2018-05-16

UChicago Information

Division(s)
Pritzker School of Molecular Engineering