Published July 21, 2011
| Version v1
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Variation in the CHI3L1 Gene Influences Serum YKL-40 Levels, Asthma Risk and Lung Function
- 1. Yale University
- 2. University of Chicago
Contributors
Patent applicants:
Description
The present invention is based on the discovery that a single nucleotide polymorphism (SNP) present the chitinase 3-like 1 gene (CHI3L1) encoding YKL-40 or a regulatory domain of the CHI3L1 gene, is associated with elevated YKL-40 levels, as well as an increased risk for developing a lung disorder, including asthma, bronchial hyperresponsivity, and/or reduced lung function.
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Additional details
Identifiers
- Patent application number
- US 74498708 A
- Patent number
- US 2011/0177963 A1
- Other
- oai:uchicago.tind.io:8608
Dates
- Patent filed
-
2008-11-26