Published March 2, 2026 | Version v1
Journal article

Behavior change intervention targeting physical activity and diet improves stress and sleep

  • 1. Northwestern University
  • 2. Rush University
  • 3. University of Chicago

Description

Background: Poor diet, low physical activity, high stress, and poor sleep are prevalent modifiable risk factors for chronic diseases. Synergistic effects of interventions targeting diet and activity on other health risk behaviors such as stress and sleep are understudied.

Purpose: To conduct a secondary data analysis to investigate whether interventions targeting diet and activity produce collateral improvements in stress and sleep.

Methods: Make Better Choices 2 was a randomized clinical trial to test a technology-assisted coaching intervention with modest incentives to improve diet and activity, as compared to a matched intervention targeting improved stress and sleep. Participants (n = 212) were adults (76.4% female, 59% non-white minority, mean age = 40.8 years) with multiple diet and activity risk behaviors. For 7 days at baseline, 3-, 6-, and 9-months, participants reported perceived sleep duration, stress, diet, and activity through a smartphone application. Outcomes were evaluated by linear mixed models. The study was registered on clinicaltrials.gov (NCT01249989).

Results: Both interventions produced significant, statistically comparable improvements in average daily stress rating (z = 1.35, p = .177). Reduction in average daily stress rating was 1.68 following diet/activity intervention (z = −12.25, P < .001) and 2.08 following stress/sleep intervention (z = −7.83, P < .001) on an 11-point Likert scale. Though changes in sleep duration for both groups were clinically meaningful, the stress/sleep intervention produced statistically larger improvements in sleep as compared to the diet/activity intervention (z = −3.79, P < .001). Sleep duration increased 26.39 minutes following diet/activity intervention (z = 3.16, P = 0.002) and 92.65 minutes following stress/sleep intervention (z = 5.912, P < 0.001).

Conclusions: Findings suggest that diet and activity behavior change interventions can effectively improve outcomes within and between the behavior domains they directly target. Future research should identify common mechanistic pathways to inform development of interventions that efficiently change multiple health behaviors implicated in chronic disease morbidity and mortality.

Additional details

Identifiers

DOI
10.1371/journal.pone.0343397
Other
oai:uchicago.tind.io:16845

Funding

National Heart Lung and Blood Institute
R01HL075451
National Heart Lung and Blood Institute
F31HL162555
National Center for Advancing Translational Sciences
UL1TR000150
National Cancer Institute
T32CA193193

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Public Health Sciences