Biological Sciences Division
Published April 18, 2019 | Version v1
Patent Open

COMPOSITIONS AND METHODS RELATED TO ANTIBODIES THAT NEUTRALIZE COAGULASE ACTIVITY DURING STAPHYLOCOCCUS AUREUS DISEASE

Creators

  • 1. University of Chicago
  • 2. Janssen Pharmaceuticals Inc.

Contributors

Patent assignee:

Description

Embodiments concern methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. Aspects include methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody that binds Coagulase (Coa). Further aspects relate to immunogenic compositions comprising at least one Staphylococcal coagulase R Domain, wherein the R Domain is 80% identical in sequence to a R Domain.

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Additional details

Identifiers

Patent application number
US 201716077213 A
Patent number
US 2019/0112342 A1
Other
oai:uchicago.tind.io:8259

Dates

Patent filed
2017-02-10

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Microbiology