Published October 9, 2014
| Version v1
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IMMUNOGENIC PROTEIN CONJUGATES AND METHOD FOR MAKING AND USING THE SAME
- 1. University of Chicago
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Patent applicants:
Description
Production of protein conjugate vaccines by use of transpeptidase enzymes, such as sortase enzymes. For example, homogenous immunoconjugates (e.g., a population of molecules having the same structure) formed by conjugating an antigenic polypeptide and a bacterial capsule component are provided. In certain aspects, methods for generating an immune response to B. anthracis by use of protective antigen-PDGA immunoconjugates are provided.
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Additional details
Identifiers
- Patent number
- US 201214237320 A
- Patent application number
- US 2014/0302084 A1
- Other
- oai:uchicago.tind.io:9513
Dates
- Patent filed
-
2012-08-05