Published December 13, 2023 | Version v1
Journal article Open

Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent

Description

Fibrosing mediastinitis (FM) is a rare, potentially progressive disease resulting from an idiosyncratic immune response to a variety of stimuli that lead to fibrous infiltration of the mediastinum and possible narrowing of the bronchovascular structures. We report an unusual case of FM in a pediatric patient presenting as myopericarditis and progressing to pericardial thickening and encasement of the mediastinal vascular structures needing surgical intervention. Imaging, including transthoracic echocardiography, cardiac computed tomography, and cardiac magnetic resonance played a crucial role in the diagnosis, assessment, and follow-up. Contrast-enhanced computed tomography can be especially helpful to demonstrate potential findings associated with FM.

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Additional details

Identifiers

DOI
10.1016/j.jaccas.2023.102161
Other
oai:uchicago.tind.io:10169

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Medicine, Pathology, Pediatrics, Radiology, Surgery