Published February 19, 2019
| Version v1
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Compositions and methods related to recombinant antibodies to histone posttranslational modifications
Creators
- 1. University of Chicago
Contributors
Patent applicant:
Description
Embodiments concern compositions and methods involving recombinant antibodies to histone post-translational modifications. The invention provides compositions and methods for histone methyltransferase assays. In certain embodiments, the compositions and methods involve a recombinant antibody that binds histone H3 fragment harboring biomarkers such as H3K9me3 mark, H3K4me3 mark, H3K36me3 mark, H3K27me3, H3K9me3 and H3S10phos or a recombinant antibody that binds histone H4 fragment harboring H4K20me3 mark.
Files
US10208110.pdf
Files
(6.3 MB)
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Additional details
Identifiers
- Patent number
- US 10208110 B2
- Patent application number
- US 201414900692 A
- Other
- oai:uchicago.tind.io:6982
Dates
- Patent filed
-
2014-06-27