Published April 1, 2021 | Version v1
Patent Open

COMPOSITIONS AND METHODS FOR INHIBITION OF FOXP3

  • 1. University of Chicago
  • 2. Dana-Farber Cancer Institute

Description

Provided herein are peptide-based therapeutics that target FOXP3 and methods of use thereof to decrease the immunosuppressive effects of Tregs and inhibit immune dysregulation, while sparring inhibition of activated cytotoxic T cells, for example, in the context of anti-tumor immune responses, autoimmunity, inflammatory conditions, etc.

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Additional details

Identifiers

Patent application number
US 201716464590 A
Patent number
US 2021/0094990 A1
Other
oai:uchicago.tind.io:9478

Dates

Patent filed
2017-12-07

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Medicine, Cancer Biology