Published January 3, 2013 | Version v1
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YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE

Description

Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.

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Additional details

Identifiers

Patent number
US 201213462478 A
Patent application number
US 2013/0005608 A1
Other
oai:uchicago.tind.io:9434

Dates

Patent filed
2012-05-02

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Molecular Genetics and Cell Biology