Published September 14, 2021 | Version v1
Patent Open

BTK mutation and ibrutinib resistance

  • 1. University of Chicago

Contributors

Patent applicant:

Description

Provided herein are mutations in Bruton's Tyrosine Kinase (BTK) that confer resistance to treatment with a BTK inhibitors, such as Ibrutinib, and compositions and methods for the treatment, diagnosis, and characterization of BTK-inhibitor-resistant cancers.

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Additional details

Identifiers

Patent number
US 11118233 B2
Patent application number
US 201716302015 A
Other
oai:uchicago.tind.io:7427

Dates

Patent filed
2017-05-18

UChicago Information

Division(s)
Biological Sciences Division
Department(s)
Medicine