Published December 6, 2016
| Version v1
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Fibronectin cradle molecules and libraries thereof
Creators
- 1. University of Chicago
Contributors
Patent applicants:
Patent assignee:
Description
The here described invention discloses a combination of a top and bottom loop binder library using the CD and the FG loops of a number of FnIII domains (FnIII) (e.g., FnIII7, FnIII10 and FnIII14) together with the surface exposed residues of the beta-sheet. The invention also pertains to a method of forming a library of FnIII domain polypeptides useful in screening for the presence of one or more polypeptides having a selected binding or enzymatic activity.
Files
US9512199.pdf
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Additional details
Identifiers
- Patent number
- US 201113813409 A
- Patent application number
- US 9512199 B2
- Other
- oai:uchicago.tind.io:8318
Dates
- Patent filed
-
2011-08-01