@article{TEXTUAL,
      recid = {9757},
      author = {Safavi, Shervin and Dwarakanath, Abhilash and Kapoor,  Vishal and Werner, Joachim and Hatsopoulos, Nicholas G. and  Logothetis, Nikos K. and Panagiotaropoulos, Theofanis I.},
      title = {Nonmonotonic spatial structure of interneuronal  correlations in prefrontal microcircuits},
      journal = {PNAS},
      address = {2018-03-27},
      number = {TEXTUAL},
      abstract = {Correlated fluctuations of single neuron discharges, on a  mesoscopic scale, decrease as a function of lateral  distance in early sensory cortices, reflecting a rapid  spatial decay of lateral connection probability and  excitation. However, spatial periodicities in horizontal  connectivity and associational input as well as an enhanced  probability of lateral excitatory connections in the  association cortex could theoretically result in  nonmonotonic correlation structures. Here, we show such a  spatially nonmonotonic correlation structure, characterized  by significantly positive long-range correlations, in the  inferior convexity of the macaque prefrontal cortex. This  functional connectivity kernel was more pronounced during  wakefulness than anesthesia and could be largely attributed  to the spatial pattern of correlated variability between  functionally similar neurons during structured visual  stimulation. These results suggest that the spatial decay  of lateral functional connectivity is not a common  organizational principle of neocortical microcircuits. A  nonmonotonic correlation structure could reflect a critical  topological feature of prefrontal microcircuits,  facilitating their role in integrative processes.},
      url = {http://knowledge.uchicago.edu/record/9757},
}