000009156 001__ 9156 000009156 005__ 20240725122326.0 000009156 024__ $$dUS 201715597588 A 000009156 024__ $$aUS 2017/0252336 A1 000009156 037__ $$aPATENT 000009156 041__ $$aEnglish 000009156 245__ $$aUSE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION 000009156 260__ $$c2017-09-07 000009156 260__ $$g2017-05-17 000009156 336__ $$aPatent 000009156 520__ $$aThe invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists. 000009156 690__ $$aBiological Sciences Division 000009156 691__ $$aAnesthesia and Critical Care 000009156 691__ $$aSurgery 000009156 7011_ $$aMoss, Jonathan$$uUniversity of Chicago 000009156 7011_ $$aLingen, Mark$$uUniversity of Chicago 000009156 7011_ $$aSingleton, Patrick A.$$uUniversity of Chicago 000009156 7011_ $$aGarcia, Joe G. N.$$uUniversity of Chicago 000009156 7011_ $$aYuan, Chun-su$$uUniversity of Chicago 000009156 7121_ $$aUniversity of Chicago 000009156 7131_ $$aUniversity of Chicago 000009156 8564_ $$94eadbd9d-afe2-4948-a842-f62b05d29169$$s2499662$$uhttps://knowledge.uchicago.edu/record/9156/files/US20170252336.pdf$$ePublic 000009156 909CO $$ooai:uchicago.tind.io:9156$$pGLOBAL_SET 000009156 983__ $$aPatent