TY - GEN AB - Methods and compositions for modulating apoptosis by acting on the c-Jun-N-terminal kinase (JNK) pathway and assays for the isolation of agents capable of modulating apoptosis, including modulators of the JNK pathway are disclosed. A method of modulating JNK pathway independent of Gadd46beta is disclosed. Methods and compositions are presented for the preparation and use of novel therapeutic compositions for modulating diseases and conditions associated with elevated or decreased apoptosis. DA - 2008-04-08 ID - 8792 L1 - https://knowledge.uchicago.edu/record/8792/files/US7354898.pdf L2 - https://knowledge.uchicago.edu/record/8792/files/US7354898.pdf L4 - https://knowledge.uchicago.edu/record/8792/files/US7354898.pdf LA - English LK - https://knowledge.uchicago.edu/record/8792/files/US7354898.pdf N2 - Methods and compositions for modulating apoptosis by acting on the c-Jun-N-terminal kinase (JNK) pathway and assays for the isolation of agents capable of modulating apoptosis, including modulators of the JNK pathway are disclosed. A method of modulating JNK pathway independent of Gadd46beta is disclosed. Methods and compositions are presented for the preparation and use of novel therapeutic compositions for modulating diseases and conditions associated with elevated or decreased apoptosis. PY - 2008-04-08 T1 - Identification of novel factors that block programmed cell death or apoptosis by targeting JNK TI - Identification of novel factors that block programmed cell death or apoptosis by targeting JNK UR - https://knowledge.uchicago.edu/record/8792/files/US7354898.pdf ER -