@article{PATENT,
      recid = {8614},
      title = {Total internal reflection fluorescence apparatus},
      number = {PATENT},
      month = {Feb},
      year = {2008},
      abstract = {Techniques are provided for illuminating a sample by using  total internal reflection (TIR) from a diffraction limited  focused annular illumination beam. The illumination forms  an affected region and an overlapping confocal region that  may have dimensions the below 1 mum. An adjustable  diffractive optical element, for example, may create a  second order Bessel profile laser beam that is focused on a  sample using a high-numerical aperture objective under TIR.  An evanescent field excites fluorescent biological material  in the confocal region, and fluorescence from the material  is analyzed in fluorescence correlation spectroscopy  system.},
      url = {http://knowledge.uchicago.edu/record/8614},
}