000008266 001__ 8266
000008266 005__ 20240725122332.0
000008266 024__ $$aUS 201314092728 A
000008266 024__ $$dUS 9944982 B2
000008266 037__ $$aPATENT
000008266 041__ $$aEnglish
000008266 245__ $$aSurface chemistry and deposition techniques
000008266 260__ $$c2018-04-17
000008266 260__ $$g2013-11-27
000008266 336__ $$aPatent
000008266 520__ $$aSurface chemistries for the visualization of labeled single molecules (analytes) with improved signal-to-noise properties are provided. To be observed, analyte molecules are bound to surface attachment features that are spaced apart on the surface such that when the analytes are labeled adjacent analytes are optically resolvable from each other. One way to express this concept is that binding elements should be spaced apart such that the Guassian point spread functions of adjacent labels do not overlap. Another way of expressing this concept is that the surface binding elements should be spaced apart by a distance equal to at least the diffraction limit for an optical label attached to the bound analytes.
000008266 690__ $$aPhysical Sciences Division
000008266 691__ $$aChemistry
000008266 7011_ $$aSchwartz, Jerrod$$uStanford University
000008266 7011_ $$aQuake, Stephen R.$$uStanford University
000008266 7011_ $$aMrksich, Milan$$uUniversity of Chicago
000008266 7121_ $$aSchwartz, Jerrod
000008266 7121_ $$aQuake, Stephen R.
000008266 7121_ $$aMrksich, Milan
000008266 7121_ $$aStanford University
000008266 7121_ $$aUniversity of Chicago
000008266 7121_ $$aCalifornia Institute of Technology
000008266 7131_ $$aCalifornia Institute of Technology
000008266 7131_ $$aUniversity of Chicago
000008266 7131_ $$aStanford University
000008266 8564_ $$9b1cf13e2-cb00-408c-b57c-ba20ad921f1d$$ePublic$$s376295$$uhttps://knowledge.uchicago.edu/record/8266/files/US9944982.pdf
000008266 909CO $$ooai:uchicago.tind.io:8266$$pGLOBAL_SET
000008266 983__ $$aPatent