@article{PATENT,
      recid = {7801},
      title = {PURINE DERIVATIVE COMPOUNDS FOR MEDICAL USE},
      number = {PATENT},
      month = {Nov},
      year = {2015},
      abstract = {A method for treatment of disease by reduction in  macrophages-mediated bacterial killing, including  administration to patients in need a compound of formula  (I): wherein A is N or CH; B is NO, or S; R1 is H,  (C1-C4)alkyl group, methyl(C1-C6)cycloalkyl group or  (C1-C6)cycloalkyl group; R2 is an aryl, arylmethyl group or  methylheteroaryl group as methylpyridine and  methylthiophene; R3 is absent when B is O or S, or is H or  (C1-C4)alkyl group when B is N; R4 is (C1-C5)alkyl group or  (C1-C4)cycloalkyl group, groups bearing a carboxylic acid  group, and (C1-C5)alkyl group or (C1-C4)cycloalkyl  substituted by hydroxyl group, halogen group or methoxy  group, when B is N, R3 and R4 can together form a 5- or  6-membered heterocycle substituted by carboxylic acid  group, substituted by a halogen atom, hydroxyl group,  methoxy group or hydroxymethyl group, or pharmaceutically  acceptable salt. Also provided are new compounds relating  to this use.},
      url = {http://knowledge.uchicago.edu/record/7801},
}