@article{THESIS,
      recid = {7529},
      author = {Peng, Cheng},
      title = {Studies of the Strategic Syntheses of Natural Products  with Contiguous All-Carbon Quaternary Stereocenters},
      publisher = {University of Chicago},
      school = {Ph.D.},
      address = {2023-08},
      number = {THESIS},
      pages = {467},
      abstract = {The synthetic studies toward natural products with  contiguous all-carbon quaternary stereocenters, including  waihoensene and bipolarolides A-D are described. By  regarding the quaternary centers as key structural elements  and carefully analyzing the challenges and opportunities  related to them, synthetic routes were designed in a  concise and reliable manner. In particular, gold-catalyzed  cyclization reactions were found to be exceptionally  powerful in the construction of contiguous quaternary  centers. A tandem gold(I)-catalyzed cyclization reaction to  form angular tricyclic structures with three contiguous  quaternary centers was discovered and further evaluated in  the syntheses of complex natural products. A thorough  literature review of the applications of gold(I)-catalysis  in the formation of all-carbon quaternary centers is also  included, with our novel insight of the importance of the  linear nature of gold(I)-complexes in such  transformations.},
      url = {http://knowledge.uchicago.edu/record/7529},
      doi = {https://doi.org/10.6082/uchicago.7529},
}