@article{TEXTUAL,
      recid = {7472},
      author = {Brown, M. Scott and Grubb, Jennifer and Zhang, Annie and  Rust, Michael J. and Bishop, Douglas K.},
      title = {Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends  of a Meiotic DNA Double Strand Break},
      journal = {PLOS Genetics},
      address = {2015-12-31},
      number = {TEXTUAL},
      abstract = {The Eukaryotic RecA-like proteins Rad51 and Dmc1 cooperate  during meiosis to promote recombination between homologous  chromosomes by repairing programmed DNA double strand  breaks (DSBs). Previous studies showed that Rad51 and Dmc1  form partially overlapping co-foci. Here we show these  Rad51-Dmc1 co-foci are often arranged in pairs separated by  distances of up to 400 nm. Paired co-foci remain prevalent  when DSBs are dramatically reduced or when strand exchange  or synapsis is blocked. Super-resolution dSTORM microscopy  reveals that individual foci observed by conventional light  microscopy are often composed of two or more substructures.  The data support a model in which the two tracts of ssDNA  formed by a single DSB separate from one another by  distances of up to 400 nm, with both tracts often bound by  one or more short (about 100 nt) Rad51 filaments and also  by one or more short Dmc1 filaments.},
      url = {http://knowledge.uchicago.edu/record/7472},
}