000007403 001__ 7403 000007403 005__ 20251007025314.0 000007403 024__ $$aUS 11270479 B2 000007403 024__ $$dUS 201716070791 A 000007403 037__ $$aPATENT 000007403 041__ $$aEnglish 000007403 245__ $$aOptimization-based reconstruction with an image-total-variation constraint in PET 000007403 260__ $$c2022-03-08 000007403 260__ $$g2017-02-13 000007403 336__ $$aPatent 000007403 520__ $$aIn an emission imaging method, emission imaging data are acquired for a subject using an emission imaging scanner (10) including radiation detectors (12). The emission imaging data are reconstructed to generate a reconstructed image by executing a constrained optimization program including a measure of data fidelity between the acquired emission imaging data an a reconstruct-image transformed by a data model of the imaging scanner to emission imaging data. During the reconstructing, each iteration of the constrained optimization program is constrained by an image variability constraint. The reconstructed image is displayed the reconstructed image on a display device. The emission imaging may be positron emission tomography (PET) imaging data, optionally acquired using a sparse detector array. The image variability constraint may be a constraint that an image total variation (image TV) of a latent image defined using a Gaussian blurring matrix be less than a maximum value. 000007403 690__ $$aBiological Sciences Division 000007403 691__ $$aRadiology 000007403 7011_ $$aPan, Xiaochuan$$uUniversity of Chicago 000007403 7011_ $$aYe, Jinghan$$uUniversity of Chicago 000007403 7011_ $$aPerkins, Amy$$uUniversity of Chicago 000007403 7011_ $$aTung, Chi-Hua$$uKoninklijke Philips N.V. 000007403 7011_ $$uUniversity of Chicago$$aZhang, Zheng 000007403 7121_ $$aKoninklijke Philips N.V. 000007403 7121_ $$aUniversity of Chicago 000007403 7131_ $$aKoninklijke Philips N.V. 000007403 7131_ $$aUniversity of Chicago 000007403 8564_ $$913aa5769-9d62-49a4-a3bf-d466d6d51d2d$$s2161305$$uhttps://knowledge.uchicago.edu/record/7403/files/US11270479.pdf$$ePublic 000007403 909CO $$ooai:uchicago.tind.io:7403$$pGLOBAL_SET 000007403 983__ $$aPatent