@article{PATENT,
      recid = {7367},
      title = {Polymer conjugate vaccines},
      number = {PATENT},
      month = {Nov},
      year = {2022},
      abstract = {Monomers and copolymers are provided that both target  antigen presenting cells (APCs) and activate toll-like  receptor (TLR) on the APCs. In some embodiments,  compositions and methods involve a polymer that targets the  mannose receptor on APCs, in addition to activating a TLR.  These can then be conjugated to protein antigens to  efficiently target antigens to DCs and simultaneously  induce the up-regulation of co-stimulatory molecules that  are essential for effective T cell activation. This  copolymer is a more efficient activator of DCs, as measured  by the surface expression of co-stimulatory molecules and  the release of proinflammatory cytokines, than the  monomeric form the TLR agonist used in the polymer  formulation. Aspects of the disclosure relate to novel  compounds, methods, and compositions for treating diseases  using the compounds, copolymers, and compositions described  herein.},
      url = {http://knowledge.uchicago.edu/record/7367},
}